Dereje Jima
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Explore the profile of Dereje Jima including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
1000
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Recent Articles
1.
Broadaway K, Brotman S, Rosen J, Currin K, Alkhawaja A, Etheridge A, et al.
Am J Hum Genet
. 2024 Aug;
111(9):1899-1913.
PMID: 39173627
Understanding the molecular mechanisms of complex traits is essential for developing targeted interventions. We analyzed liver expression quantitative-trait locus (eQTL) meta-analysis data on 1,183 participants to identify conditionally distinct signals....
2.
Witherspoon J, Hall J, Jima D, Atkins H, Wamsley N, Major M, et al.
Redox Biol
. 2024 Jul;
75:103261.
PMID: 38963974
Squamous cell carcinomas (SCCs), including lung, head & neck, bladder, and skin SCCs often display constitutive activation of the KEAP1-NRF2 pathway. Constitutive activation is achieved through multiple mechanisms, including activating...
3.
Harris H, Friedman C, Starling A, Dabelea D, Johnson S, Fuemmeler B, et al.
Appetite
. 2023 Oct;
191:107086.
PMID: 37844693
The etiology of childhood appetitive traits is poorly understood. Early-life epigenetic processes may be involved in the developmental programming of appetite regulation in childhood. One such process is DNA methylation...
4.
Vidal A, Chandramouli S, Marchesoni J, Brown N, Liu Y, Murphy S, et al.
Hepatol Commun
. 2023 Sep;
7(10).
PMID: 37755881
Background: Tobacco smoking during pregnancy is associated with metabolic dysfunction in children, but mechanistic insights remain limited. Hypomethylation of cg05575921 in the aryl hydrocarbon receptor repressor (AHRR) gene is associated...
5.
Harris H, Friedman C, Starling A, Dabelea D, Johnson S, Fuemmeler B, et al.
bioRxiv
. 2023 Jul;
PMID: 37503194
Childhood appetitive traits are consistently associated with obesity risk, and yet their etiology is poorly understood. Appetitive traits are complex phenotypes which are hypothesized to be influenced by both genetic...
6.
Newell A, Jima D, Reading B, Patisaul H
Toxicol Sci
. 2023 Jul;
195(1):103-122.
PMID: 37399109
Toxicogenomics is a critical area of inquiry for hazard identification and to identify both mechanisms of action and potential markers of exposure to toxic compounds. However, data generated by these...
7.
Ligaba-Osena A, Salehin M, Numan M, Wang X, Choi S, Jima D, et al.
Sci Rep
. 2022 Nov;
12(1):19552.
PMID: 36380130
Calcium (Ca) is one of the essential mineral nutrients for plant growth and development. However, the effects of long-term Ca deficiency in orphan crops such as Tef [(Eragrostis tef) (Zucc.)...
8.
Watson A, Carmona Baez A, Jima D, Reif D, Ding J, Roberts R, et al.
Toxicol Sci
. 2022 Nov;
191(1):149-162.
PMID: 36370075
Differentiation of multipotent mesenchymal stem cells (MSCs) into bone-forming osteoblasts requires strict coordination of transcriptional pathways. Aryl hydrocarbon receptor ligands, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), have been shown to alter osteoblast...
9.
Zhou Y, Gallins P, Etheridge A, Jima D, Scholl E, Wright F, et al.
Sci Rep
. 2022 Sep;
12(1):15151.
PMID: 36071064
In this study, we generated whole-transcriptome RNA-Seq from n = 192 genotyped liver samples and used these data with existing data from the GTEx Project (RNA-Seq) and previous liver eQTL...
10.
Moylan C, Mavis A, Jima D, Maguire R, Bashir M, Hyun J, et al.
Epigenetics
. 2022 Feb;
17(11):1446-1461.
PMID: 35188871
Non-Alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in children. Epigenetic alterations, such as through DNA methylation (DNAm), may link adverse childhood exposures and fatty...