Dennis J Grab
Overview
Explore the profile of Dennis J Grab including associated specialties, affiliations and a list of published articles.
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40
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1013
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Recent Articles
1.
Tawana M, Onyiche T, Ramatla T, Nkhebenyane S, Grab D, Thekisoe O
Microorganisms
. 2025 Jan;
12(12.
PMID: 39770629
This study presents a systematic review and meta-analysis approach of species prevalence studies in animal and human hosts published between 1980 and 2020 in South Africa. Extensive searches were conducted...
2.
Londono A, Farner J, Dillon M, Grab D, Kim Y, Scorpio D, et al.
PLoS Negl Trop Dis
. 2024 Feb;
18(2):e0011993.
PMID: 38408129
Spotted fever group rickettsiae are tick-borne obligate intracellular bacteria that infect microvascular endothelial cells. Humans and mammalian infection results in endothelial cell barrier dysfunction and increased vascular permeability. We previously...
3.
Kim Y, Clemens E, Farner J, Londono-Barbaran A, Grab D, Dumler J
Biochem Biophys Res Commun
. 2023 Apr;
663:96-103.
PMID: 37121130
The tick-borne bacterium Rickettsia parkeri is an obligate intracellular pathogen that belongs to spotted fever group rickettsia (SFGR). The SFG pathogens are characterized by their ability to infect and rapidly...
4.
Costa T, Goundry A, Morrot A, Grab D, Mottram J, Lima A
Int J Mol Sci
. 2023 Jan;
24(1.
PMID: 36614101
The protozoan causes Human African Trypanosomiasis, also known as sleeping sickness, and penetrates the central nervous system, leading to meningoencephalitis. The Cathepsin L-like cysteine peptidase of has been implicated in...
5.
Kim Y, Wang J, Clemens E, Grab D, Dumler J
Front Cell Infect Microbiol
. 2022 Jun;
12:828605.
PMID: 35719343
, a tick-borne obligately intracellular bacterium of neutrophils, causes human granulocytic anaplasmosis. Ankyrin A (AnkA), an effector protein with multiple ankyrin repeats (AR) is injected via type IV-secretion into the...
6.
Levy D, Goundry A, Laires R, Costa T, Novo C, Grab D, et al.
PLoS Negl Trop Dis
. 2021 Jun;
15(6):e0009526.
PMID: 34153047
Trypanosoma brucei rhodesiense is one of the causative agents of Human African Trypanosomiasis (HAT), known as sleeping sickness. The parasite invades the central nervous system and causes severe encephalitis that...
7.
Bista S, Singh P, Bernard Q, Yang X, Hart T, Lin Y, et al.
J Infect Dis
. 2019 Nov;
221(9):1438-1447.
PMID: 31758693
Borrelia burgdorferi conserved gene products BB0406 and BB0405, members of a common B. burgdorferi paralogous gene family, share 59% similarity. Although both gene products can function as potential porins, only...
8.
Huang H, Lennikov A, Saddala M, Gozal D, Grab D, Khalyfa A, et al.
FASEB J
. 2019 Oct;
33(12):13695-13709.
PMID: 31585507
We report that placental growth factor (PlGF) negatively affects the endothelial cell (EC) barrier function through a novel regulatory mechanism. The PlGF mAb promotes (but recombinant protein disrupts) EC barrier...
9.
Grab D, Nikolskaia O, Courtioux B, Thekisoe O, Magez S, Bogorad M, et al.
PLoS Negl Trop Dis
. 2019 Aug;
13(8):e0007631.
PMID: 31425540
Objective: Where human African trypanosomiasis (HAT) patients are seen, failure to microscopically diagnose infections by Trypanosoma brucei gambiense in blood smears and/or cerebrospinal fluid (CSF) in the critical early stages...
10.
Saddala M, Lennikov A, Grab D, Liu G, Tang S, Huang H
Sci Rep
. 2018 Nov;
8(1):16728.
PMID: 30425286
Placental growth factor (PlGF or PGF), a member of the vascular endothelial growth factor (VEGF) sub-family, plays a crucial role in pathological angiogenesis and inflammation. However, the underlying molecular mechanisms...