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Denise Frosina

Explore the profile of Denise Frosina including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 2560
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Recent Articles
1.
Ng S, Stephan C, Do M, Frosina D, Jungbluth A, Busam K, et al.
J Cutan Pathol . 2024 Dec; 52(3):244-249. PMID: 39698761
Background: Mpox (formerly known as monkeypox), a zoonotic disease caused by Monkeypox virus (MPXV), has become an international outbreak since May 2022. Mpox often presents with a mild systemic illness...
2.
Xu B, Jungbluth A, Frosina D, Alabkaa A, Serrette R, Qin H, et al.
Head Neck Pathol . 2024 Nov; 18(1):123. PMID: 39589616
Purpose: BSND is a chloride channel subunit that is expressed in the normal salivary gland. We aimed to validate the utility of BSND immunohistochemistry in the differential diagnosis of oncocytic...
3.
Chen J, Hernandez E, Frosina D, Ruh P, Ariyan C, Busam K, et al.
Am J Dermatopathol . 2024 Jul; 46(9):563-571. PMID: 39008470
Melanocyte differentiation antigens refer to molecules expressed in cells of melanocytic lineage such as gp100/PMEL, tyrosinase, and Melan-A. Corresponding antibodies such as HMB45, T311, and A103 have become key immunohistochemical...
4.
Gupta A, Gazzo A, Selenica P, Safonov A, Pareja F, da Silva E, et al.
bioRxiv . 2024 May; PMID: 38746158
Acquired genetic alterations commonly drive resistance to endocrine and targeted therapies in metastatic breast cancer , however the underlying processes engendering these diverse alterations are largely uncharacterized. To identify the...
5.
Liu Y, Sardana R, Nemirovsky D, Frosina D, Jungbluth A, Johnson W, et al.
Blood Adv . 2024 Apr; 8(12):3064-3075. PMID: 38593227
Although significant progress has been made in understanding the genetic basis of primary hemophagocytic lymphohistiocytosis (HLH), the pathogenesis of secondary HLH, the more prevalent form, remains unclear. Among the various...
6.
Febres-Aldana C, Chang J, Jungbluth A, Adusumilli P, Bodd F, Frosina D, et al.
Mod Pathol . 2024 Jan; 37(3):100420. PMID: 38185249
9p21 deletions involving MTAP/CDKN2A genes are detected in diffuse pleural mesotheliomas (DPM) but are absent in benign mesothelial proliferations. Loss of MTAP expression by immunohistochemistry (IHC) is well accepted as...
7.
Zhong E, Brogi E, DAlfonso T, Wen H, Frosina D, Cheung N, et al.
Appl Immunohistochem Mol Morphol . 2021 Sep; 30(2):113-118. PMID: 34545847
The glycosphingolipid disialoganglioside GD2 is a cell surface-associated antigen expressed on tumors of neuroectodermal origin that serves as a target of immunotherapy in select cancer types. Information about the expression...
8.
Grabenstetter A, Jungbluth A, Frosina D, Hoda R, Dos Anjos C, Patil S, et al.
Am J Surg Pathol . 2021 Jun; 45(9):1274-1281. PMID: 34115674
Immunotherapy for the treatment of programmed death-ligand 1 (PD-L1) positive locally advanced or metastatic triple negative breast cancer may benefit patients with metaplastic breast cancer (MpBC). Previous study of PD-L1...
9.
Lezcano C, Muller A, Frosina D, Hernandez E, Geronimo J, Busam K, et al.
Int J Surg Pathol . 2021 Apr; 29(8):826-835. PMID: 33890816
Cancer-testis (CT) antigens were identified by their ability to elicit T- or B-cell immune responses in the autologous host. They are typically expressed in a wide variety of neoplasms and...
10.
Segura S, Stolnicu S, Boros M, Park K, Ramirez P, Salvo G, et al.
Appl Immunohistochem Mol Morphol . 2021 Feb; 29(7):527-533. PMID: 33587450
The Silva pattern of invasion, recently introduced to stratify patients at risk for lymph node metastases in human papillomavirus-associated endocervical adenocarcinomas (HPVAs), can only be assessed in cone and loop...