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Denis Laurent

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Articles 24
Citations 313
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Recent Articles
11.
Aguilar-Briseno J, Upasani V, Ter Ellen B, Moser J, Pauzuolis M, Ruiz-Silva M, et al.
Nat Commun . 2020 Jun; 11(1):3177. PMID: 32576819
Vascular permeability and plasma leakage are immune-pathologies of severe dengue virus (DENV) infection, but the mechanisms underlying the exacerbated inflammation during DENV pathogenesis are unclear. Here, we demonstrate that TLR2,...
12.
Upasani V, Vo H, Ung S, Heng S, Laurent D, Choeung R, et al.
Front Immunol . 2019 Nov; 10:2500. PMID: 31736948
Dengue is a mosquito-borne viral disease caused by dengue virus (DENV). The disease is endemic to more than 100 countries with 390 million dengue infections per year. Humoral immune responses...
13.
Duong V, Choeung R, Gorman C, Laurent D, Crabol Y, Mey C, et al.
J Gen Virol . 2017 Aug; 98(9):2287-2296. PMID: 28840803
Japanese encephalitis remains the most important cause of viral encephalitis in humans in several southeast Asian countries, including Cambodia, causing at least 65 000 cases of encephalitis per year. This...
14.
Horwood P, Duong V, Laurent D, Mey C, Sothy H, Santy K, et al.
Emerg Microbes Infect . 2017 May; 6(5):e35. PMID: 28536430
Acute meningoencephalitis (AME) is associated with considerable morbidity and mortality in children in developing countries. Clinical specimens were collected from children presenting with AME at two Cambodian paediatric hospitals to...
15.
Crabol Y, Pean P, Mey C, Duong V, Richner B, Laurent D, et al.
Int J Infect Dis . 2017 Apr; 59:69-76. PMID: 28438677
Objectives: In this study, we document the clinical characteristics and investigated risk factors for uncomplicated and severe forms of EV-A71 disease in Cambodian children. Methods: From March to July 2014...
16.
Ly S, Horwood P, Chan M, Rith S, Sorn S, Oeung K, et al.
Emerg Infect Dis . 2017 Jan; 23(2):300-303. PMID: 28098551
Thirty-five human influenza A(H5N1) cases were reported in Cambodia during 2013-2014 after emergence of a clade 1.1.2 reassortant virus. We tested 881 villagers and found 2 cases of pauci- or...
17.
Duong V, Mey C, Eloit M, Zhu H, Danet L, Huang Z, et al.
Emerg Microbes Infect . 2016 Sep; 5(9):e104. PMID: 27651091
Human enterovirus 71 (EV-A71) causes hand, foot and mouth disease (HFMD). EV-A71 circulates in many countries and has caused large epidemics, especially in the Asia-Pacific region, since 1997. In April...
18.
Rith S, Davis C, Duong V, Sar B, Horm S, Chin S, et al.
J Virol . 2014 Sep; 88(23):13897-909. PMID: 25210193
Human infections with influenza A(H5N1) virus in Cambodia increased sharply during 2013. Molecular characterization of viruses detected in clinical specimens from human cases revealed the presence of mutations associated with...
19.
Schopfer K, Rieder H, Bodmer T, Steinlin-Schopfer J, Chantana Y, Studer P, et al.
Eur J Pediatr . 2013 Sep; 173(3):331-6. PMID: 24065457
Unlabelled: This study aimed at determining the sensitivity of a whole blood interferon-γ release assay (IGRA) among children with microbiologically confirmed tuberculosis in a high-burden country. Children with a diagnosis...
20.
Duong V, Andries A, Ngan C, Sok T, Richner B, Asgari-Jirhandeh N, et al.
Emerg Infect Dis . 2012 Nov; 18(12):2066-9. PMID: 23171736
Chikungunya virus (CHIKV), probably Asian genotype, was first detected in Cambodia in 1961. Despite no evidence of acute or recent CHIKV infections since 2000, real-time reverse transcription PCR of serum...