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Denis J P David

Explore the profile of Denis J P David including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 128
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Recent Articles
1.
Guilloux J, David D, Xia L, Nguyen H, Rainer Q, Guiard B, et al.
Neuropharmacology . 2011 Feb; 61(3):478-88. PMID: 21333660
Selective serotonin (5-HT) re-uptake inhibitors (SSRIs) are commonly used in the treatment of generalized anxiety disorder in Humans. However, because only few animal models display overt anxious-like behavior, detailed preclinical...
2.
Chenu F, David D, Leroux-Nicollet I, Le Maitre E, Gardier A, Bourin M
J Psychiatry Neurosci . 2008 Nov; 33(6):541-50. PMID: 18982177
Objective: We sought to demonstrate whether the specific activation of serotonin1B (5-HT1B) heteroreceptors by systemic or local administration of the selective 5-HT1B receptor agonist anpirtoline could mediate antidepressant-like effects in...
3.
Guiard B, David D, Deltheil T, Chenu F, Le Maitre E, Renoir T, et al.
Int J Neuropsychopharmacol . 2007 Jun; 11(1):79-92. PMID: 17559709
Growing evidence supports the involvement of brain-derived neurotrophic factor (BDNF) in mood disorders and the mechanism of action of antidepressant drugs. However, the relationship between BDNF and serotonergic signalling is...
4.
Guilloux J, David D, Guiard B, Chenu F, Reperant C, Toth M, et al.
Neuropsychopharmacology . 2006 Feb; 31(10):2162-72. PMID: 16452992
Selective serotonin reuptake inhibitors like paroxetine (Prx) often requires 4-6 weeks to achieve clinical benefits in depressed patients. Pindolol shortens this delay and it has been suggested that this effect...
5.
Renard C, Dailly E, David D, Hascoet M, Bourin M
Fundam Clin Pharmacol . 2003 Aug; 17(4):449-55. PMID: 12914547
Microdialysis, binding and behavioural studies have shown that the dopaminergic system plays a role in antidepressant treatment. It has been suggested that stress may provoke a modification in dopamine (DA)...