Dengke K Ma
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Explore the profile of Dengke K Ma including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Ji Z, Wang B, Chandra R, Liu J, Yang S, Long Y, et al.
bioRxiv
. 2025 Feb;
PMID: 39975403
Visible light influences a range of physiological processes, yet how animals respond to it independently of the visual system remains largely unknown. Here, we uncover a previously undescribed light-induced transcriptional...
2.
Jiang W, Cao Y, Xue Y, Ji Y, Winer B, Chandra R, et al.
Proc Natl Acad Sci U S A
. 2025 Jan;
122(5):e2417515122.
PMID: 39874294
The ε4 variant of human apolipoprotein E () is a key genetic risk factor for neurodegeneration in Alzheimer's disease and elevated all-cause mortality in humans. Understanding the factors and mechanisms...
3.
Ji Z, Pandey T, De Belly H, Wang B, Weiner O, Tang Y, et al.
bioRxiv
. 2024 Jul;
PMID: 38948723
Oxidative protein folding in the endoplasmic reticulum (ER) is essential for all eukaryotic cells yet generates hydrogen peroxide (HO), a reactive oxygen species (ROS). The ER-transmembrane protein that provides reducing...
4.
Li Q, Liu Y, Wu J, Zhu Z, Fan J, Zhai L, et al.
Leukemia
. 2024 Jun;
38(8):1751-1763.
PMID: 38909089
Aberrations in the Hedgehog (Hh) signaling pathway are significantly prevailed in various cancers, including B-cell lymphoma. A critical facet of Hh signal transduction involves the dynamic regulation of the suppressor...
5.
Jiang W, Cao Y, Xue Y, Ji Y, Winer B, Zhang M, et al.
bioRxiv
. 2024 Mar;
PMID: 38464138
Mortality rate increases with age and can accelerate upon extrinsic or intrinsic damage to individuals. Identifying factors and mechanisms that curb population mortality rate has wide-ranging implications. Here, we show...
6.
Pandey T, Wang B, Wang C, Zu J, Deng H, Shen K, et al.
Cell Rep
. 2024 Mar;
43(3):113899.
PMID: 38446666
Insulin-mechanistic target of rapamycin (mTOR) signaling drives anabolic growth during organismal development; its late-life dysregulation contributes to aging and limits lifespans. Age-related regulatory mechanisms and functional consequences of insulin-mTOR remain...
7.
Jiang W, De Belly H, Wang B, Wong A, Kim M, Oh F, et al.
Sci Adv
. 2024 Jan;
10(4):eadj3880.
PMID: 38266092
Early-life stress experiences can produce lasting impacts on organismal adaptation and fitness. How transient stress elicits memory-like physiological effects is largely unknown. Here, we show that early-life thermal stress strongly...
8.
Pandey T, Kalluraya C, Wang B, Xu T, Huang X, Guang S, et al.
EMBO J
. 2023 Nov;
42(24):e114835.
PMID: 37953666
Natural selection drives the acquisition of organismal resilience traits to protect against adverse environments. Horizontal gene transfer (HGT) is an important evolutionary mechanism for the acquisition of novel traits, including...
9.
Fluorescent reporter of Parkin: Regulators of its abundance and role in autophagy-lysosomal dynamics
Vozdek R, Wang B, Li K, Pramstaller P, Hicks A, Ma D
Open Res Eur
. 2023 Oct;
2:23.
PMID: 37811477
Parkin, which when mutated leads to early-onset Parkinson's disease, acts as an E3 ubiquitin ligase. How Parkin is regulated for selective protein and organelle targeting is not well understood. Here,...
10.
Wang R, Xiao L, Pan J, Bao G, Zhu Y, Zhu D, et al.
Nat Commun
. 2023 Sep;
14(1):5984.
PMID: 37752106
Induction of hypothermia during hibernation/torpor enables certain mammals to survive under extreme environmental conditions. However, pharmacological induction of hypothermia in most mammals remains a huge challenge. Here we show that...