Deng-Ke Niu
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Explore the profile of Deng-Ke Niu including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
413
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Recent Articles
1.
Liu Z, Hu E, Niu D
Microbiol Spectr
. 2023 Apr;
11(3):e0340922.
PMID: 37022199
CRISPR-Cas systems provide adaptive immunity for prokaryotic cells by recognizing and eliminating the recurrent genetic invaders whose sequences had been captured in a prior infection and stored in the CRISPR...
2.
Ma M, Xia J, Shu K, Niu D
Biol Direct
. 2022 Jun;
17(1):13.
PMID: 35659725
Background: The evolution of spliceosomal introns has been widely studied among various eukaryotic groups. Researchers nearly reached the consensuses on the pattern and the mechanisms of intron losses and gains...
3.
Lan X, Liu Z, Niu D
Front Microbiol
. 2022 Mar;
13:773114.
PMID: 35300480
Although performing adaptive immunity, CRISPR-Cas systems are present in only 40% of bacterial genomes. We observed an abrupt increase of bacterial CRISPR-Cas abundance at around 45°C. Phylogenetic comparative analyses confirmed...
4.
Hu E, Lan X, Liu Z, Gao J, Niu D
BMC Genomics
. 2022 Feb;
23(1):110.
PMID: 35139824
Background: GC pairs are generally more stable than AT pairs; GC-rich genomes were proposed to be more adapted to high temperatures than AT-rich genomes. Previous studies consistently showed positive correlations...
5.
Li X, Fang C, Zhao J, Zhou X, Ni Z, Niu D
BMC Genomics
. 2020 Jul;
21(1):452.
PMID: 32611311
Background: Although horizontal gene transfer (HGT) is a widely accepted force in the evolution of prokaryotic genomes, its role in the evolution of eukaryotic genomes remains hotly debated. Some bdelloid...
6.
Ni Z, Zhou X, Aslam S, Niu D
Front Genet
. 2019 Dec;
10:1208.
PMID: 31867040
Copy number changes in protein-coding genes are detrimental if the consequent changes in protein concentrations disrupt essential cellular functions. The dosage sensitivity of transcription factor (TF) genes is particularly interesting...
7.
Aslam S, Lan X, Zhang B, Chen Z, Wang L, Niu D
BMC Evol Biol
. 2019 Jan;
19(1):35.
PMID: 30691392
Background: Among the four bases, guanine is the most susceptible to damage from oxidative stress. Replication of DNA containing damaged guanines results in G to T mutations. Therefore, the mutations...
8.
Chen H, Wang Q, Yin Y, Li S, Niu D, Wang H
Int J Antimicrob Agents
. 2017 Dec;
51(4):655-658.
PMID: 29247687
Staphylococcus aureus small colony variants (SCVs) can cause persistent infections. However, the genomes and transcriptomes of S. aureus SCVs remain poorly understood. A pair of isogenic wild-type and SCV methicillin-resistant...
9.
Ma M, Lan X, Niu D
PeerJ
. 2016 Aug;
4:e2272.
PMID: 27547574
The origin and subsequent accumulation of spliceosomal introns are prominent events in the evolution of eukaryotic gene structure. However, the mechanisms underlying intron gain remain unclear because there are few...
10.
Ma M, Zhu T, Li X, Lan X, Liu H, Yang Y, et al.
Biol Direct
. 2016 Jul;
10(1):24.
PMID: 27392031
Unlabelled: In this study, we identified 19 intron losses, including 11 precise intron losses (PILs), six imprecise intron losses (IILs), one de-exonization, and one exon deletion in tomato and potato,...