Demetrios A Arvanitis
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Explore the profile of Demetrios A Arvanitis including associated specialties, affiliations and a list of published articles.
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37
Citations
658
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Recent Articles
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Vafiadaki E, Haghighi K, Arvanitis D, Kranias E, Sanoudou D
Int J Mol Sci
. 2022 Jul;
23(13).
PMID: 35805951
Phospholamban (PLN), a key modulator of Ca-homeostasis, inhibits sarcoplasmic reticulum (SR) calcium-ATPase (SERCA2a) and regulates cardiac contractility. The human mutation R14del has been identified in arrhythmogenic cardiomyopathy patients worldwide and...
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Brandenburg S, Pawlowitz J, Steckmeister V, Subramanian H, Uhlenkamp D, Scardigli M, et al.
J Mol Cell Cardiol
. 2022 Jan;
165:141-157.
PMID: 35033544
Axial tubule junctions with the sarcoplasmic reticulum control the rapid intracellular Ca-induced Ca release that initiates atrial contraction. In atrial myocytes we previously identified a constitutively increased ryanodine receptor (RyR2)...
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Haghighi K, Gardner G, Vafiadaki E, Kumar M, Green L, Ma J, et al.
J Pers Med
. 2021 Jul;
11(6).
PMID: 34204946
The inherited mutation (R14del) in the calcium regulatory protein phospholamban (PLN) is linked to malignant ventricular arrhythmia with poor prognosis starting at adolescence. However, the underlying early mechanisms that may...
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Vafiadaki E, Arvanitis D, Eliopoulos A, Kranias E, Sanoudou D
Int J Mol Sci
. 2020 Dec;
21(24).
PMID: 33339131
The cytoskeleton has a primary role in cardiomyocyte function, including the response to mechanical stimuli and injury. The small heat shock protein 20 (Hsp20) conveys protective effects in cardiac muscle...
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Chalatsa I, Arvanitis D, Koulakiotis N, Giagini A, Skaltsounis A, Papadopoulou-Daifoti Z, et al.
Front Neurosci
. 2019 Apr;
13:249.
PMID: 30971876
L. natural compounds have been extensively used in traditional medicine for thousands of years. Recent research evidence is now emerging in support of its therapeutic potential for different pathologies including...
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Arvanitis D, Vafiadaki E, Johnson D, Kranias E, Sanoudou D
Front Physiol
. 2018 Oct;
9:1379.
PMID: 30319456
Sudden unexpected cardiac death (SCD) accounts for up to half of all-cause mortality of heart failure patients. Standardized cardiology tools such as electrocardiography, cardiac imaging, electrophysiological and serum biomarkers cannot...
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Chalatsa I, Arvanitis D, Mikropoulou E, Giagini A, Papadopoulou-Daifoti Z, Aligiannis N, et al.
J Alzheimers Dis
. 2018 Jun;
64(3):787-800.
PMID: 29914017
Background: Natural products are a significantly underutilized source of potential treatments against human disease. Alzheimer's disease (AD) is a prime example of conditions that could be amenable to such treatments...
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Arvanitis D, Vafiadaki E, Papalouka V, Sanoudou D
Biochim Biophys Acta Mol Cell Res
. 2017 Sep;
1864(12):2308-2321.
PMID: 28867610
Muscle Lim Protein (MLP) is a protein with multiple functional roles in striated muscle physiology and pathophysiology. Herein, we demonstrate that MLP directly binds to slow, fast, and cardiac myosin-binding...