Delphine Meffre
Overview
Explore the profile of Delphine Meffre including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
289
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0
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Recent Articles
1.
Ahmed M, Kakunuri T, Peris L, Meffre D, Yilmaz E, Grewing L, et al.
Brain Commun
. 2025 Feb;
7(1):fcae473.
PMID: 39926615
Lesions in the CNS are frequently associated to a detrimental inflammatory reaction. In autoimmune neurodegenerative diseases, a proliferation-inducing ligand (APRIL) produced by CNS-infiltrating inflammatory cells binds to chondroitin sulphate proteoglycans...
2.
Padilla-Ferrer A, Carrete A, Simon A, Meffre D, Jafarian-Tehrani M
Brain Res
. 2024 Mar;
1834:148888.
PMID: 38548249
A Disintegrin And Metalloprotease 10 (ADAM10), is able to control several important physiopathological processes through the shedding of a large number of protein substrates. Although ADAM10 plays a crucial role...
3.
Carrete A, Padilla-Ferrer A, Simon A, Meffre D, Jafarian-Tehrani M
Neuroscience
. 2020 Nov;
455:240-250.
PMID: 33246058
Demyelination is a well-known pathological process in CNS disorders such as multiple sclerosis (MS). It provokes progressive axonal degeneration and functional impairments and no efficient therapy is presently available to...
4.
Shackleford G, Makoukji J, Grenier J, Liere P, Meffre D, Massaad C
Biochem Pharmacol
. 2020 Mar;
175:113892.
PMID: 32155468
No abstract available.
5.
Chierto E, Simon A, Castoldi F, Meffre D, Cristinziano G, Sapone F, et al.
Mol Neurobiol
. 2018 Oct;
56(6):4231-4248.
PMID: 30298339
Increasing findings suggest that demyelination may play an important role in the pathophysiology of brain injury, but the exact mechanisms underlying such damage are not well known. Mechanical tensile strain...
6.
Llufriu-Daben G, Meffre D, Massaad C, Jafarian-Tehrani M
J Neurosci Methods
. 2018 Sep;
311:385-393.
PMID: 30253198
Background: Traumatic brain injury (TBI) induces significant cognitive deficits correlated with white matter injury, involving both axonal and myelin damage. Several models of TBI ex vivo are available to mimic...
7.
Shackleford G, Sampathkumar N, Hichor M, Weill L, Meffre D, Juricek L, et al.
Proc Natl Acad Sci U S A
. 2018 Jan;
115(6):E1319-E1328.
PMID: 29351992
Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor involved in xenobiotic metabolism. Plexiform neurofibromas (PNFs) can transform into malignant peripheral nerve sheath tumors (MPNSTs) that are resistant to existing...
8.
Llufriu-Daben G, Carrete A, Chierto E, Mailleux J, Camand E, Simon A, et al.
Neurobiol Dis
. 2017 Sep;
109(Pt A):11-24.
PMID: 28923597
Remyelination is an endogenous regenerative process of myelin repair in the central nervous system (CNS) with limited efficacy in demyelinating disorders. As strategies enhancing endogenous remyelination become a therapeutic challenge,...
9.
Shackleford G, Grenier J, Habib W, Massaad C, Meffre D
J Steroid Biochem Mol Biol
. 2016 Mar;
169:61-68.
PMID: 26940358
Liver X Receptors (LXRs) α and β are nuclear receptors able to bind oxidative forms of cholesterol. They play important roles in the central nervous system (CNS), through their implication...
10.
Meffre D, Shackleford G, Hichor M, Gorgievski V, Tzavara E, Trousson A, et al.
Proc Natl Acad Sci U S A
. 2015 May;
112(24):7587-92.
PMID: 26023184
The identification of new pathways governing myelination provides innovative avenues for remyelination. Liver X receptors (LXRs) α and β are nuclear receptors activated by oxysterols that originated from the oxidation...