Delbert G Gillespie
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Explore the profile of Delbert G Gillespie including associated specialties, affiliations and a list of published articles.
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64
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935
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Recent Articles
1.
Jackson E, Gillespie D, Mi Z, Birder L, Tofovic S
Sci Rep
. 2024 Sep;
14(1):22652.
PMID: 39349636
The metabolic syndrome is characterized by obesity, insulin resistance, dyslipidemia and hypertension and predisposes to cardiorenal injury. Here, we tested our hypothesis that 8-aminoguanine, an endogenous purine, exerts beneficial effects...
2.
Morris B, Hixson E, Klamar-Blain C, Gillespie D, Abebe K, Rinaldo C, et al.
J Leukoc Biol
. 2024 Aug;
117(1).
PMID: 39217408
Twelve weeks of dipyridamole increased extracellular adenosine levels and decreased T cell activation in people with human immunodeficiency virus (HIV). In this analysis, we investigated the effect of dipyridamole on...
3.
Jackson E, Gillespie D, Mi Z
Hypertension
. 2023 Feb;
80(5):981-994.
PMID: 36802842
Background: The endogenous purine 8-aminoguanine induces diuresis/natriuresis/glucosuria by inhibiting PNPase (purine nucleoside phosphorylase); however, mechanistic details are unknown. Methods: Here, we further explored in rats 8-aminoguanine's effects on renal excretory...
4.
Jackson E, Menshikova E, Ritov V, Gillespie D, Mi Z
Biochem Pharmacol
. 2022 May;
201:115076.
PMID: 35551915
Background: 8-Aminoguanine exerts natriuretic and antihypertensive activity. Whether and how "free" 8-aminoguanine exists in vivo is unclear. Because 8-nitroguanosine is naturally occurring, we tested the hypothesis that 8-aminoguanine can arise...
5.
Jackson E, Mi Z, Gillespie D, Cheng D, Tofovic S
J Am Heart Assoc
. 2021 Mar;
10(6):e020088.
PMID: 33682436
Background The long-term effects of dipeptidyl peptidase 4 (DPP4) inhibitors on blood pressure and cardiovascular and renal health remain controversial. Herein, we investigated the extended (>182 days) effects of DPP4...
6.
Mallarino-Haeger C, Abebe K, Jackson E, Zyhowski A, Klamar-Blain C, Cyktor J, et al.
J Acquir Immune Defic Syndr
. 2020 Nov;
85(5):665-669.
PMID: 33177477
Background: We had previously conducted a double-blind, randomized placebo-controlled, partial cross-over trial showing that 12 weeks of dipyridamole decreased CD8 T-cell activation among treated HIV(+) individuals by increasing extracellular adenosine...
7.
Ludwig N, Yerneni S, Menshikova E, Gillespie D, Jackson E, Whiteside T
Sci Rep
. 2020 Aug;
10(1):14027.
PMID: 32807847
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
8.
Ludwig N, Gillespie D, Reichert T, Jackson E, Whiteside T
Cancers (Basel)
. 2020 Jun;
12(6).
PMID: 32560461
Body fluids of patients with head and neck squamous cell carcinoma (HNSCC) are enriched in exosomes that reflect properties of the tumor. The aim of this study was to determine...
9.
Ludwig N, Azambuja J, Rao A, Gillespie D, Jackson E, Whiteside T
Purinergic Signal
. 2020 May;
16(2):231-240.
PMID: 32440820
Exosomes, small-sized extracellular vesicles, carry components of the purinergic pathway. The production by cells of exosomes carrying this pathway remains poorly understood. Here, we asked whether type 1, 2A, or...
10.
Ludwig N, Yerneni S, Azambuja J, Gillespie D, Menshikova E, Jackson E, et al.
Angiogenesis
. 2020 May;
23(4):599-610.
PMID: 32419057
Rationale: One hallmark of tumor-derived exosomes (TEX) is the promotion of cancer progression by stimulating angiogenesis. This study was performed to evaluate the role of adenosine receptors in TEX-induced angiogenesis....