Deepraj Ghosh
Overview
Explore the profile of Deepraj Ghosh including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
250
Followers
0
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Recent Articles
1.
Howes A, Dea N, Ghosh D, Krishna K, Wang Y, Li Y, et al.
APL Bioeng
. 2024 Jun;
8(2):026119.
PMID: 38855444
Senescent cell accumulation in the pulmonary niche is associated with heightened susceptibility to age-related disease, tissue alterations, and ultimately a decline in lung function. Our current knowledge of senescent cell-extracellular...
2.
Mejia Pena C, Skipper T, Hsu J, Schechter I, Ghosh D, Dawson M
Sci Rep
. 2023 Nov;
13(1):19232.
PMID: 37932310
More than 75% of epithelial ovarian cancer (EOC) patients experience disease recurrence after initial treatment, highlighting our incomplete understanding of how chemoresistant populations evolve over the course of EOC progression...
3.
Ghosh D, Hsu J, Soriano K, Mejia Pena C, Lee A, Dizon D, et al.
Cancers (Basel)
. 2023 Jun;
15(12).
PMID: 37370796
Metastatic progression of epithelial ovarian cancer (EOC) involves the partial epithelial-to-mesenchymal transition (EMT) of cancer cells in the primary tumor and dissemination into peritoneal fluid. In part to the high...
4.
Lee A, Ghosh D, Koh I, Dawson M
Aging (Albany NY)
. 2023 Feb;
15(5):1237-1256.
PMID: 36842089
Radiation-induced fibrosis is a common side effect of radiotherapy, which is the most common treatment for cancer. However, radiation also causes p53-mediated cell cycle arrest, prolonged expression of p21, and...
5.
Xuan B, Ghosh D, Dawson M
Semin Cancer Biol
. 2021 May;
81:64-72.
PMID: 33992783
Polyploid giant cancer cells (PGCCs) are a commonly observed histological feature of human tumors and are particularly prominent in late stage and drug resistant cancers. The chromosomal duplication conferred by...
6.
Dawson M, Xuan B, Hsu J, Ghosh D
Int Rev Cell Mol Biol
. 2021 May;
360:1-31.
PMID: 33962748
The tumor microenvironment is a complex milieu that dictates the growth, invasion, and metastasis of cancer cells. Both cancer and stromal cells in the tumor tissue encounter and adapt to...
7.
Xuan B, Ghosh D, Jiang J, Shao R, Dawson M
Proc Natl Acad Sci U S A
. 2020 Oct;
117(43):26756-26765.
PMID: 33046658
Polyploidal giant cancer cells (PGCCs) are multinucleated chemoresistant cancer cells found in heterogeneous solid tumors. Due in part to their apparent dormancy, the effect of PGCCs on cancer progression has...
8.
Ali M, Wu Y, Ghosh D, Do B, Chen K, Dawson M, et al.
ACS Nano
. 2020 Sep;
14(9):12260.
PMID: 32902953
No abstract available.
9.
Lee A, Ghosh D, Quach N, Schroeder D, Dawson M
Sci Rep
. 2020 May;
10(1):8686.
PMID: 32457479
Exosomes are cell-secreted microvesicles that play important roles in epithelial ovarian cancer (EOC) progression, as they are constantly secreted into ascites fluids. While cells spontaneously release exosomes, alterations in intracellular...
10.
Ghosh D, Mejia Pena C, Quach N, Xuan B, Lee A, Dawson M
J Cell Sci
. 2020 Jan;
133(2).
PMID: 31932504
Mesenchymal stem cells (MSCs) are essential for the regenerative process; however, biological aging and environmental stress can induce senescence - an irreversible state of growth arrest - that not only...