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Deepa Machiah

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Articles 8
Citations 188
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Recent Articles
1.
Peterson M, Joyner C, Lapp S, Brady J, Wood J, Cabrera-Mora M, et al.
Front Cell Infect Microbiol . 2022 Jul; 12:888496. PMID: 35811680
poses a health threat throughout Southeast Asian communities and currently causes most cases of malaria in Malaysia. This zoonotic parasite species has been studied in (rhesus monkeys) as a model...
2.
Birdwell L, Levesque D, Machiah D, Gumber S
J Med Primatol . 2022 Mar; 51(3):155-164. PMID: 35357015
Background: Diabetes mellitus type 2 has been linked to pancreatic islet amyloid deposition in humans and nonhuman primates. The authors hypothesized that diabetic primates would have significant differences in pathology...
3.
Peterson M, Joyner C, Brady J, Wood J, Cabrera-Mora M, Saney C, et al.
Malar J . 2021 Dec; 20(1):486. PMID: 34969401
Background: Kra monkeys (Macaca fascicularis), a natural host of Plasmodium knowlesi, control parasitaemia caused by this parasite species and escape death without treatment. Knowledge of the disease progression and resilience...
4.
Peterson M, Joyner C, Cordy R, Salinas J, Machiah D, Lapp S, et al.
Open Forum Infect Dis . 2019 Apr; 6(3):ofz021. PMID: 30937329
Background: can cause severe malaria with multisystem organ dysfunction and death. Clinical reports suggest that parasite accumulation in tissues may contribute to pathogenesis and disease severity, but direct evidence is...
5.
Zimmerman M, Quicke K, Oneal J, Arora N, Machiah D, Priyamvada L, et al.
Cell Host Microbe . 2018 Nov; 24(5):731-742.e6. PMID: 30439342
Zika virus (ZIKV), which emerged in regions endemic to dengue virus (DENV), is vertically transmitted and results in adverse pregnancy outcomes. Antibodies to DENV can cross-react with ZIKV, but whether...
6.
Sinclair C, Bommakanti G, Gardinassi L, Loebbermann J, Johnson M, Hakimpour P, et al.
Science . 2017 Aug; 357(6355):1014-1021. PMID: 28798047
Antigen-presenting cells (APCs) occupy diverse anatomical tissues, but their tissue-restricted homeostasis remains poorly understood. Here, working with mouse models of inflammation, we found that mechanistic target of rapamycin (mTOR)-dependent metabolic...
7.
Mula R, Machiah D, Holland L, Wang X, Parihar H, Sharma A, et al.
PLoS One . 2016 Apr; 11(4):e0153620. PMID: 27101012
Autoimmune vasculitis is an endothelial inflammatory disease that results from the deposition of immune-complexes (ICs) in blood vessels. The interaction between Fcgamma receptors (FcγRs) expressed on inflammatory cells with ICs...
8.
Shashidharamurthy R, Machiah D, Aitken J, Putty K, Srinivasan G, Chassaing B, et al.
Arthritis Rheum . 2013 Jan; 65(4):1064-73. PMID: 23280250
Objective: Lipocalin 2 (LCN-2) is an innate immune protein that is expressed by a variety of cells and is highly up-regulated during several pathologic conditions, including immune complex (IC)-mediated inflammatory/autoimmune...