Declan G Bates
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Explore the profile of Declan G Bates including associated specialties, affiliations and a list of published articles.
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72
Citations
405
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Recent Articles
1.
Yu H, Saffaran S, Tonelli R, Laffey J, Esquinas A, de Lima L, et al.
Crit Care
. 2025 Mar;
29(1):101.
PMID: 40055757
Background: Early identification of patients with acute hypoxemic respiratory failure (AHRF) who are at risk of failing high-flow nasal cannula (HFNC) therapy could facilitate closer monitoring, and timely adjustment/escalation of...
2.
Shamohammadi H, Weaver L, Saffaran S, Tonelli R, Laviola M, Laffey J, et al.
Respir Res
. 2025 Jan;
26(1):9.
PMID: 39780218
Introduction And Objectives: High flow nasal cannula (HFNC) therapy is an increasingly popular mode of non-invasive respiratory support for the treatment of patients with acute hypoxemic respiratory failure (AHRF). Previous...
3.
Mannan A, Darlington A, Tanaka R, Bates D
Nat Commun
. 2025 Jan;
16(1):279.
PMID: 39747041
Bacteria can be engineered to manufacture chemicals, but it is unclear how to optimally engineer a single cell to maximise production performance from batch cultures. Moreover, the performance of engineered...
4.
Sharafutdinov K, Fritsch S, Iravani M, Farhadi Ghalati P, Saffaran S, Bates D, et al.
IEEE Open J Eng Med Biol
. 2024 Aug;
5:611-620.
PMID: 39184970
Machine learning (ML) technologies that leverage large-scale patient data are promising tools predicting disease evolution in individual patients. However, the limited generalizability of ML models developed on single-center datasets, and...
5.
Weaver L, Shamohammadi H, Saffaran S, Tonelli R, Laviola M, Laffey J, et al.
Crit Care Med
. 2024 Aug;
52(9):e473-e484.
PMID: 39145711
Objectives: To clarify the mechanistic basis for the success or failure of noninvasive ventilation (NIV) in acute hypoxemic respiratory failure (AHRF). Design: We created digital twins based on mechanistic computational...
6.
Mistry S, Scott T, Jugg B, Perrott R, Saffaran S, Bates D
Toxicol Lett
. 2023 Dec;
391:45-54.
PMID: 38092154
We present the first computational model of the pathophysiological consequences of phosgene-induced lung injury in porcine subjects. Data from experiments previously performed in several cohorts of large healthy juvenile female...
7.
Barakat C, Sharafutdinov K, Busch J, Saffaran S, Bates D, Hardman J, et al.
Diagnostics (Basel)
. 2023 Jun;
13(12).
PMID: 37370993
Acute Respiratory Distress Syndrome (ARDS) is a condition that endangers the lives of many Intensive Care Unit patients through gradual reduction of lung function. Due to its heterogeneity, this condition...
8.
Paulino N, Foo M, de Greef T, Kim J, Bates D
Bioengineering (Basel)
. 2023 Apr;
10(4).
PMID: 37106653
Chemical reaction networks can be utilised as basic components for nucleic acid feedback control systems' design for Synthetic Biology application. DNA hybridisation and programmed strand-displacement reactions are effective primitives for...
9.
Bowyer J, Chakravarti D, Wong W, Bates D
Eng Biol
. 2023 Mar;
4(1):10-19.
PMID: 36970230
Inducible genetic switches based on tyrosine recombinase-based DNA excision are a promising platform for the regulation and control of chimeric antigen receptor (CAR) T cell activity in cancer immunotherapy. These...
10.
Daudre-Vignier C, Bates D, Scott T, Hardman J, Laviola M
Resuscitation
. 2023 Mar;
186:109758.
PMID: 36871922
Objective: We aimed to use a high-fidelity computational model that captures key interactions between the cardiovascular and pulmonary systems to investigate whether current CPR protocols could potentially be improved. Methods:...