DeBroski R Herbert
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Explore the profile of DeBroski R Herbert including associated specialties, affiliations and a list of published articles.
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65
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2671
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Recent Articles
11.
Herbert D, Stoltzfus J, Rossi H, Abraham D
Mol Biochem Parasitol
. 2022 Aug;
251:111511.
PMID: 36007683
The gastrointestinal (GI) nematode Strongyloides stercoralis (S.s.) causes human strongyloidiasis, a potentially life-threatening disease that currently affects over 600 million people globally. The uniquely pernicious aspect of S.s. infection, as...
12.
Rahman M, McFadden G, Ruthel G, Herbert D, Freedman B, Greenberg R, et al.
Exp Parasitol
. 2022 May;
239:108263.
PMID: 35598646
Schistosomiasis is a devastating disease caused by parasitic flatworms of the genus Schistosoma. Praziquantel (PZQ), the current treatment of choice, is ineffective against immature worms and cannot prevent reinfection. The...
13.
Kumar B, Field N, Kim D, Dar A, Chen Y, Suresh A, et al.
Nat Commun
. 2022 May;
13(1):2786.
PMID: 35589717
Antigen encounter directs CD4 T cells to differentiate into T helper or regulatory cells. This process focuses the immune response on the invading pathogen and limits tissue damage. Mechanisms that...
14.
Inclan-Rico J, Rossi H, Herbert D
Mucosal Immunol
. 2022 May;
15(6):1199-1211.
PMID: 35538230
Helminths are remarkably successful parasites that can invade various mammalian hosts and establish chronic infections that can go unnoticed for years despite causing severe tissue damage. To complete their life...
15.
Musaigwa F, Kamdem S, Mpotje T, Mosala P, Abdel Aziz N, Herbert D, et al.
PLoS Pathog
. 2022 Feb;
18(2):e1010327.
PMID: 35157732
Schistosomiasis is a potentially lethal parasitic disease that profoundly impacts systemic immune function in chronically infected hosts through mechanisms that remain unknown. Given the immunoregulatory dysregulation experienced in infected individuals,...
16.
Bais S, Norwillo A, Ruthel G, Herbert D, Freedman B, Greenberg R
Biochimie
. 2022 Jan;
194:108-117.
PMID: 34990770
Schistosomiasis is a neglected tropical disease caused by parasitic flatworms of the genus Schistosoma. Mono-therapeutic treatment of this disease with the drug praziquantel, presents challenges such as inactivity against immature...
17.
18.
Rossi H, Ortiz-Carpena J, Tucker D, Vaughan A, Mangalmurti N, Cohen N, et al.
Am J Respir Cell Mol Biol
. 2021 Nov;
66(3):252-259.
PMID: 34784491
Tissue damage in the upper and lower airways caused by mechanical abrasion, noxious chemicals, or pathogenic organisms must be followed by rapid restorative processes; otherwise, persistent immunopathology and disease may...
19.
Adewale B, Heintz J, Pastore C, Rossi H, Hung L, Rahman N, et al.
PLoS Negl Trop Dis
. 2021 Oct;
15(10):e0009550.
PMID: 34662329
Helminth infections, including hookworms and Schistosomes, can cause severe disability and death. Infection management and control would benefit from identification of biomarkers for early detection and prognosis. While animal models...
20.
Damen M, Stankiewicz T, Park S, Helsley R, Chan C, Moreno-Fernandez M, et al.
Int J Obes (Lond)
. 2021 Jul;
45(11):2377-2387.
PMID: 34302121
Objective: The risks of excess sugar intake in addition to high-fat diet consumption on immunopathogenesis of obesity-associated metabolic diseases are poorly defined. Interleukin-4 (IL-4) and IL-13 signaling via IL-4Rα regulates...