Deborah C Molrine
Overview
Explore the profile of Deborah C Molrine including associated specialties, affiliations and a list of published articles.
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12
Citations
574
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Recent Articles
1.
Lambert P, Ambrosino D, Andersen S, Baric R, Black S, Chen R, et al.
Vaccine
. 2020 Jun;
38(31):4783-4791.
PMID: 32507409
A novel coronavirus (CoV), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in late 2019 in Wuhan, China and has since spread as a global pandemic. Safe and effective vaccines...
2.
Gogtay N, Munshi R, Narayana D, Mahendra B, Kshirsagar V, Gunale B, et al.
Clin Infect Dis
. 2017 Oct;
66(3):387-395.
PMID: 29020321
Background: Lack of access to rabies immunoglobulin (RIG) contributes to high rabies mortality. A recombinant human monoclonal antibody (SII RMAb) was tested in a postexposure prophylaxis (PEP) regimen in comparison...
3.
Smith H, Saia G, Lobikin M, Tiwari T, Cheng S, Molrine D
Hum Vaccin Immunother
. 2017 Sep;
13(11):2738-2741.
PMID: 28933665
There is a global shortage of equine-derived diphtheria anti-toxin (DAT) for diphtheria treatment. There are few existing data on serum antibody concentrations and neutralizing activity post-treatment to support development of...
4.
Smith H, Cheslock P, Leney M, Barton B, Molrine D
Virulence
. 2016 Apr;
7(6):660-8.
PMID: 27070129
Prompt administration of anti-toxin reduces mortality following Corynebacterium diphtheriae infection. Current treatment relies upon equine diphtheria anti-toxin (DAT), with a 10% risk of serum sickness and rarely anaphylaxis. The global...
5.
Souders C, Maynard S, Yan J, Wang Y, Boatright N, Sedan J, et al.
Int J Mol Sci
. 2015 Jun;
16(6):12436-53.
PMID: 26042465
Angiogenic biomarkers, including soluble fms-like tyrosine kinase 1 (sFlt1), are thought to be predictors of preeclampsia onset; however, improvement is needed before a widespread diagnostic test can be utilized. Here...
6.
Babcock G, Iyer S, Smith H, Wang Y, Rowley K, Ambrosino D, et al.
PLoS One
. 2014 Jun;
9(6):e100325.
PMID: 24956119
Chronic hepatitis C virus (HCV) infection is the most common cause of end-stage liver disease, often leading to liver transplantation, in which case circulating virions typically infect the transplanted liver...
7.
Morin T, Broering T, Leav B, Blair B, Rowley K, Boucher E, et al.
PLoS Pathog
. 2012 Sep;
8(8):e1002895.
PMID: 22952447
Hepatitis C virus (HCV) infection is a leading cause of liver transplantation and there is an urgent need to develop therapies to reduce rates of HCV infection of transplanted livers....
8.
Lowy I, Molrine D, Leav B, Blair B, Baxter R, Gerding D, et al.
N Engl J Med
. 2010 Jan;
362(3):197-205.
PMID: 20089970
Background: New therapies are needed to manage the increasing incidence, severity, and high rate of recurrence of Clostridium difficile infection. Methods: We performed a randomized, double-blind, placebo-controlled study of two...
9.
Antin J, Guinan E, Avigan D, Soiffer R, Joyce R, Martin V, et al.
Biol Blood Marrow Transplant
. 2005 Mar;
11(3):213-22.
PMID: 15744240
Patients undergoing autologous hematopoietic stem cell transplantation (autoHCT) are at increased risk for infection with Streptococcus pneumoniae and have impaired antibody responses to pneumococcal polysaccharide vaccines. We performed this study...
10.
Molrine D
Pediatr Transplant
. 2003 Feb;
7 Suppl 3:76-85.
PMID: 12603698
Investigations over the past decade have documented that there is a decline in immunity to vaccine preventable diseases in many SCT recipients. The majority of immunization studies conducted in SCT...