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Debing Xiang

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Articles 25
Citations 664
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Recent Articles
1.
Wang X, Xu Z, Wang J, Wu C, Zhang L, Qian C, et al.
Adv Sci (Weinh) . 2025 Feb; :e2410630. PMID: 39943694
Chemoresistance and metastasis are the main obstacles to the clinical success of anticancer treatment and are responsible for most cancer deaths. Developing effective approaches to reverse chemoresistance and inhibit metastasis...
2.
Yin J, Pei Z, Wu C, Liu J, Huang J, Xia R, et al.
Mol Carcinog . 2024 Dec; 64(3):513-525. PMID: 39692268
Cutaneous squamous cell carcinoma (cSCC) is a common type of cutaneous cancer globally. M2 macrophage-derived exosomes (M2 exosomes) facilitate the development of cancer. Ferroptosis, a newly uncovered form of cell...
3.
Liang R, Liu Z, Li B, Xiang D, Wu C
Recent Pat Anticancer Drug Discov . 2024 Jun; PMID: 38835131
Background: Globally, colorectal cancer (CRC) is known as the primary cause of mortality. Recent studies have reported that long non-coding RNAs (lncRNAs) are essential in assessing the survival of CRC...
4.
Huang C, Wang J, Xiang J, Wu C, Wang F, Chen J, et al.
Recent Pat Anticancer Drug Discov . 2024 May; PMID: 38716545
Objective: The objective of this study is to investigate the expression and regulatory mechanisms of A disintegrin and metalloproteinase domain 12 (ADAM12) in colorectal cancer (CRC) tissues and cells. Methods:...
5.
Wang X, Zhang H, Chen X, Wu C, Ding K, Sun G, et al.
Acta Biomater . 2023 May; 166:42-68. PMID: 37257574
In order to achieve targeted delivery of anticancer drugs, efficacy improvement, and side effect reduction, various types of nanoparticles are employed. However, their therapeutic effects are not ideal. This phenomenon...
6.
Zhang Z, Lian X, Yue H, Xiang D, Niu Z
Thorac Cancer . 2023 Apr; 14(16):1492-1499. PMID: 37096455
Introduction: The lymph node metastasis stage of lung cancer is an important decisive factor in the need for postoperative adjuvant treatment and the difference between stage IIIa and stage IIIB...
7.
Wu C, Sun G, Wang F, Chen J, Zhan F, Lian X, et al.
Sci Rep . 2022 Dec; 12(1):22496. PMID: 36577753
Colorectal cancer (CRC) is among the most prominent causes of cancer-associated mortality in the world, with chemoresistance representing one of the leading causes of treatment failure. However, the mechanisms governing...
8.
Long S, Wang J, Weng F, Pei Z, Zhou S, Sun G, et al.
Front Pharmacol . 2022 Nov; 13:1005915. PMID: 36408224
5-Fluorouracil (5-FU) chemoresistance is a persistent impediment to the efficient treatment of many types of cancer, yet the molecular mechanisms underlying such resistance remain incompletely understood. Here we found CRC...
9.
Long S, Wang J, Weng F, Xiang D, Sun G
Front Oncol . 2022 May; 12:889159. PMID: 35574325
In prior reports, extracellular matrix protein 1 (ECM1) upregulation has been reported in colorectal cancer (CRC) patient tumor tissues, and has been suggested to be related to the metastatic progression...
10.
Huang L, Chen J, Quan J, Xiang D
Bioengineered . 2021 Jul; 12(1):3065-3076. PMID: 34224305
Rosmarinic acid (RA), a naturally occurring polyphenolic compound, exerts multiple biological properties including anti-cancer. The metalloprotease, a disintegrin and metalloproteinase 17 (ADAM17), can activate ligands of the epidermal growth factor...