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De-Yu Chen

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Citations 221
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Recent Articles
1.
Meng J, Zhang L, Wang Z, Zhao X, Bai H, Wang Y, et al.
World J Clin Cases . 2024 Nov; 12(32):6563-6565. PMID: 39554900
Gastroduodenal tuberculosis (GD-TB) is exceptionally rare. The clinical manifestations of gastrointestinal TB are diverse and non-specific, which makes diagnosis difficult, leading to delayed diagnosis and high mortality. As a peer-reviewer...
2.
Meng J, Wang Z, Zhang L, Chen D, Wang Y, Bai H, et al.
World J Clin Cases . 2024 Oct; 12(29):6266-6270. PMID: 39417056
Fecal incontinence is a common symptom among patients with rectal prolapse. Pudendal nerve terminal motor latency (PNTML) testing can serve as a reference indicator for predicting the outcomes of rectal...
3.
Meng J, Wang Z, Zhao X, Wang Y, Chen D, Liu D, et al.
World J Clin Oncol . 2024 Jul; 15(6):667-673. PMID: 38946830
Colorectal cancer (CRC) is the third most common cancer worldwide and the second most common cause of cancer death. Nanotherapies are able to selectively target the delivery of cancer therapeutics,...
4.
Zhu M, Shen J, Fei L, Chen D
Zhonghua Nan Ke Xue . 2021 Dec; 27(6):499-505. PMID: 34914288
Objective: To investigate the role of occludin in tight junction (TJ) in vitro. Methods: We constructed RNA interfering lentiviral vectors and transfected them into TM4 cells. Then we detected their...
5.
Shen J, Zhu M, Fei L, Chen D
Zhonghua Nan Ke Xue . 2021 Dec; 27(1):11-16. PMID: 34914275
Objective: To study the transcription factors of the spermatogenesis-related promoter mir-122-5p. Methods: SP1 and GATA4 were predicted as the possible transcription factors of the mir-122-5p promoter by bioinformatics analysis, followed...
6.
Pu S, Zhang Y, Lu N, Chen D
Zhonghua Nan Ke Xue . 2021 Dec; 27(8):685-693. PMID: 34914239
Objective: To establish a testicular Occludin gene knockout model in mice and observe the phenotypic changes. Methods: Occludin-floxed (genotype Floxp/-) mice were constructed based on the Cre/loxp system, which were...
7.
Meng J, Yin Z, Zhang Y, Zhang Y, Zhao X, Zhai Q, et al.
World J Gastrointest Surg . 2021 Jun; 13(5):443-451. PMID: 34122734
Background: The most common causes of outlet obstructive constipation (OOC) are rectocele and internal rectal prolapse. The surgical methods for OOC are diverse and difficult, and the postoperative complications and...
8.
Wang X, Hu L, Qin W, Yang Q, Chen D, Li Q, et al.
Nat Commun . 2021 Jan; 12(1):174. PMID: 33420030
The immunosuppressive microenvironment that is shaped by hepatic metastatic pancreatic ductal adenocarcinoma (PDAC) is essential for tumor cell evasion of immune destruction. Neutrophils are important components of the metastatic tumor...
9.
Tan X, Chen D, Ding J, Wu J
Zhonghua Nan Ke Xue . 2020 Dec; 26(8):675-680. PMID: 33377726
Objective: To analyze the functions of the two extracellular loops of occludin in the tight junction of TM4 cells in mice. Methods: Using genetic engineering, we separately or simultaneously deleted...
10.
Sun X, Wang Y, Sun J, Xu X, Kong Q, Chen Y, et al.
J Orthop Surg (Hong Kong) . 2020 Dec; 28(3):2309499020975213. PMID: 33355038
Purpose: The study aimed to develop an evidence-based expert consensus statement on diagnosis and treatment of cervical ossification posterior longitudinal ligament (OPLL). Method: Delphi method was used to perform such...