De-Hua Cheng
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Explore the profile of De-Hua Cheng including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
73
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Recent Articles
1.
Che J, Wu H, Zeng S, Wu Y, Dai J, Cheng D, et al.
Asian J Androl
. 2023 Dec;
26(2):175-182.
PMID: 38048167
Phospholipase C zeta (PLCζ) is a key sperm-borne oocyte-activating factor that triggers Ca 2+ oscillations and the subsequent block to polyspermy following gamete fusion. Mutations in PLCZ1 , the gene...
2.
Hu H, Yang X, Cheng D, Li X, He W, Hu X, et al.
Yi Chuan
. 2023 Mar;
45(1):88-95.
PMID: 36927641
Duchenne/Becker muscular dystrophy (DMD/BMD) is one of the most common progressive muscular dystrophy diseases with X-linked recessive inheritance. It is mainly caused by the deletion, duplication and point mutation of...
3.
Wang X, Wu C, Hao D, Zhang J, Tan C, Cheng D, et al.
BMC Med Genomics
. 2021 Mar;
14(1):82.
PMID: 33731094
Background: Cryptic balanced translocations often evade detection by conventional cytogenetics. The preimplantation genetic testing (PGT) technique can be used to help carriers of balanced translocations give birth to healthy offspring;...
4.
Tan Y, Tan Y, Cheng D
Mol Cytogenet
. 2020 May;
13:15.
PMID: 32391085
Background: Apparently balanced chromosome rearrangements (ABCRs) in non-affected individuals are well-known to possess high reproductive risks such as infertility, abnormal offspring, and pregnancy loss. However, caution should be exercised in...
5.
Liao H, Ouyang Q, Zhang S, Cheng D, Lu G, Lin G
J Assist Reprod Genet
. 2016 Jan;
33(2):255-63.
PMID: 26727933
Purpose: This study aimed to derive heteroparental normal karyotypic human embryonic stem cells (hESCs) from microsurgically corrected tripronuclear (3PN) zygotes. Methods: After sequential culture for 5-6 days, embryos developed from...
6.
Xu F, Zhang Y, Cheng D, Tan K, Zhong C, Lu G, et al.
Mol Cytogenet
. 2014 Oct;
7(1):64.
PMID: 25324898
Background: Copy Number Variants (CNVs) is a new molecular frontier in clinical genetics. CNVs in 1p36 are usually pathogenic and have attracted the attention of cytogeneticists worldwide. None of 1p36...
7.
Zhou D, Lin G, Zeng S, Xiong B, Xie P, Cheng D, et al.
Arch Toxicol
. 2014 May;
89(1):33-45.
PMID: 24838295
How to maintain the genetic integrity of cultured human embryonic stem (hES) cells is raising crucial concerns for future clinical use in regenerative medicine. Mitomycin C(MMC), a DNA damage agent,...
8.
Cheng D, Gong F, Tan K, Lu C, Lin G, Lu G, et al.
Reprod Biomed Online
. 2013 May;
27(1):89-95.
PMID: 23664816
Two unrelated couples came to the Reproductive and Genetic Hospital of Citic-Xiangya to ask for reproductive guidance. One couple had an affected son and the other couple had secondary infertility....
9.
Hu J, Tan K, Cheng D, Li L, Lu G, Tan Y
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
. 2013 Mar;
30(1):87-90.
PMID: 23450488
Objective: To determine the karyotype of a boy suspected to have Cri du Chat syndrome with severe clinical manifestations, and to assess the recurrence risk for his family. Methods: High-resolution...
10.
Cheng D, Gong F, Lu C, Li L, Lu G, Tan Y
J Assist Reprod Genet
. 2012 Sep;
29(11):1299-304.
PMID: 23001237
No abstract available.