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De-Chen Yu

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Articles 8
Citations 68
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Recent Articles
1.
Su K, Yu D, Cao X, Li P, Chang L, Yu X, et al.
Stem Cell Rev Rep . 2024 Aug; 20(8):2268-2282. PMID: 39212824
Bone marrow mesenchymal stem cell (BMSC)-derived exosomes possess therapeutic potential against degenerative diseases. This study aimed to investigate the effects of BMSC-derived exosomes on intervertebral disc degeneration (IVDD) and explore...
2.
Gao X, Zhang X, Zhang R, Yu D, Chen X, Hu Y, et al.
J Mater Chem B . 2022 Jul; 10(30):5696-5722. PMID: 35852563
As our research on the physiopathology of intervertebral disc degeneration (IVD degeneration, IVDD) has advanced and tissue engineering has rapidly evolved, cell-, biomolecule- and nucleic acid-based hydrogel grafting strategies have...
3.
Hu Y, Zhang X, Lin M, Zhou H, Cong M, Chen X, et al.
Curr Stem Cell Res Ther . 2022 Apr; 18(2):163-173. PMID: 35466881
A common surgical disease, intervertebral disc degeneration (IVDD), is increasing at an alarming rate in younger individuals. Repairing damaged intervertebral discs (IVDs) and promoting IVD tissue regeneration at the molecular...
4.
Yu D, Chen X, Zhou H, Yu D, Yu X, Hu Y, et al.
Mol Biol Rep . 2022 Jan; 49(4):3055-3064. PMID: 35032258
Background: Although osteosarcoma (OS) is the most common malignant bone tumor, the biological mechanism underlying its incidence and improvement remains unclear. This study investigated early diagnosis and treatment objectives using...
5.
Zhang X, Chen X, Qi J, Zhou H, Zhao X, Hu Y, et al.
Curr Gene Ther . 2021 Oct; 22(4):291-302. PMID: 34636308
Bone Marrow Mesenchymal Stem Cells (BMSCs), multidirectional cells with self-renewal capacity, can differentiate into many cell types and play essential roles in tissue healing and regenerative medicine. Cell experiments and...
6.
Zhang R, Zhang X, Lu Y, Hu Y, Chen X, Yu D, et al.
Brain Res Bull . 2021 Aug; 176:85-92. PMID: 34418462
Objectives: Postmenopausal osteoporosis (PMO) and osteoporotic fracture seriously impair human health in developed countries. The present study aims to explore whether sensory nerves, calcitonin gene-related peptide (CGRP), and brain-derived serotonin...
7.
Zhang X, Hu Y, Cheng P, Zhou H, Chen X, Wu D, et al.
Int J Med Sci . 2021 Jul; 18(13):2799-2813. PMID: 34220308
Intervertebral disc (IVD) degeneration (IDD) is a multifactorial pathological process associated with low back pain (LBP). The pathogenesis is complicated, and the main pathological changes are IVD cell apoptosis and...
8.
Yu D, Chen X, Li X, Zhou H, Yu D, Yu X, et al.
Sci Rep . 2021 May; 11(1):11165. PMID: 34045512
The spindle and kinetochore-associated protein complex (Ska) is an essential component in chromosome segregation. It comprises three proteins (Ska1, Ska2, and Ska3) with theorized roles in chromosomal instability and tumor...