Davy Maddelein
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Explore the profile of Davy Maddelein including associated specialties, affiliations and a list of published articles.
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10
Citations
105
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Recent Articles
1.
Boone M, Ramasamy P, Zuallaert J, Bouwmeester R, Van Moer B, Maddelein D, et al.
Nat Commun
. 2023 Feb;
14(1):1072.
PMID: 36828852
No abstract available.
2.
Boone M, Ramasamy P, Zuallaert J, Bouwmeester R, Van Moer B, Maddelein D, et al.
Nat Commun
. 2021 Nov;
12(1):6414.
PMID: 34741024
While transcriptome- and proteome-wide technologies to assess processes in protein biogenesis are now widely available, we still lack global approaches to assay post-ribosomal biogenesis events, in particular those occurring in...
3.
Gupta S, De Puysseleyr V, Van der Heyden J, Maddelein D, Lemmens I, Lievens S, et al.
Bioinformatics
. 2017 Apr;
33(9):1424-1425.
PMID: 28453684
Summary: Protein-protein interaction (PPI) studies have dramatically expanded our knowledge about cellular behaviour and development in different conditions. A multitude of high-throughput PPI techniques have been developed to achieve proteome-scale...
4.
Vu L, Stes E, Van Bel M, Nelissen H, Maddelein D, Inze D, et al.
J Proteome Res
. 2016 Sep;
15(12):4304-4317.
PMID: 27643528
Protein phosphorylation is one of the most common post-translational modifications (PTMs), which can regulate protein activity and localization as well as protein-protein interactions in numerous cellular processes. Phosphopeptide enrichment techniques...
5.
Verheggen K, Maddelein D, Hulstaert N, Martens L, Barsnes H, Vaudel M
J Proteome Res
. 2015 Oct;
15(3):707-12.
PMID: 26510693
The use of proteomics bioinformatics substantially contributes to an improved understanding of proteomes, but this novel and in-depth knowledge comes at the cost of increased computational complexity. Parallelization across multiple...
6.
Degroeve S, Maddelein D, Martens L
Nucleic Acids Res
. 2015 May;
43(W1):W326-30.
PMID: 25990723
We present an MS(2) peak intensity prediction server that computes MS(2) charge 2+ and 3+ spectra from peptide sequences for the most common fragment ions. The server integrates the Unimod...
7.
Maddelein D, Colaert N, Buchanan I, Hulstaert N, Gevaert K, Martens L
Nucleic Acids Res
. 2015 Apr;
43(W1):W543-6.
PMID: 25897125
The iceLogo web server and SOAP service implement the previously published iceLogo algorithm. iceLogo builds on probability theory to visualize protein consensus sequences in a format resembling sequence logos. Peptide...
8.
Vandermarliere E, Maddelein D, Hulstaert N, Stes E, Di Michele M, Gevaert K, et al.
J Proteome Res
. 2015 Mar;
14(4):1987-90.
PMID: 25728987
Proteins are dynamic molecules; they undergo crucial conformational changes induced by post-translational modifications and by binding of cofactors or other molecules. The characterization of these conformational changes and their relation...
9.
Gonnelli G, Stock M, Verwaeren J, Maddelein D, De Baets B, Martens L, et al.
J Proteome Res
. 2015 Feb;
14(4):1792-8.
PMID: 25714903
A growing number of proteogenomics and metaproteomics studies indicate potential limitations of the application of the "decoy" database paradigm used to separate correct peptide identifications from incorrect ones in traditional...
10.
Colaert N, Maddelein D, Impens F, Van Damme P, Plasman K, Helsens K, et al.
Nucleic Acids Res
. 2012 Oct;
41(Database issue):D333-7.
PMID: 23093603
We here present The Online Protein Processing Resource (TOPPR; http://iomics.ugent.be/toppr/), an online database that contains thousands of published proteolytically processed sites in human and mouse proteins. These cleavage events were...