Davis R Ingram
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Explore the profile of Davis R Ingram including associated specialties, affiliations and a list of published articles.
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47
Citations
1037
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Recent Articles
11.
Lamhamedi-Cherradi S, Maitituoheti M, Menegaz B, Krishnan S, Vetter A, Camacho P, et al.
Nat Commun
. 2022 Jun;
13(1):3057.
PMID: 35650195
Desmoplastic small round cell tumor (DSRCT) is an aggressive, usually incurable sarcoma subtype that predominantly occurs in post-pubertal young males. Recent evidence suggests that the androgen receptor (AR) can promote...
12.
Zullow H, Sankar A, Ingram D, Guerra D, DAvino A, Collings C, et al.
Mol Cell
. 2022 Apr;
82(9):1737-1750.e8.
PMID: 35390276
Mammalian SWI/SNF (mSWI/SNF or BAF) ATP-dependent chromatin remodeling complexes play critical roles in governing genomic architecture and gene expression and are frequently perturbed in human cancers. Transcription factors (TFs), including...
13.
Molina E, Chim L, Lamhamedi-Cherradi S, Mohiuddin S, McCall D, Cuglievan B, et al.
Oncotarget
. 2022 Mar;
13:521-533.
PMID: 35284040
Osteosarcoma (OS) is a genetically diverse bone cancer that lacks a consistent targetable mutation. Recent studies suggest the IGF/PI3K/mTOR pathway and YAP/TAZ paralogs regulate cell fate and proliferation in response...
14.
Kochat V, Raman A, Landers S, Tang M, Schulz J, Terranova C, et al.
Acta Neuropathol
. 2021 Jul;
142(3):565-590.
PMID: 34283254
Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that frequently harbor genetic alterations in polycomb repressor complex 2 (PRC2) components-SUZ12 and EED. Here, we show that PRC2 loss...
15.
Schaefer I, Lundberg M, Demicco E, Przybyl J, Matusiak M, Chibon F, et al.
Cancer
. 2021 Mar;
127(15):2666-2673.
PMID: 33788262
Background: Leiomyosarcoma (LMS) is the most common soft tissue and uterine sarcoma, but no standard therapy is available for recurrent or metastatic LMS. TP53, p16/RB1, and PI3K/mTOR pathway dysregulations are...
16.
Warmke L, Tinkham E, Ingram D, Lazar A, Panse G, Wang W
Am J Clin Pathol
. 2020 Nov;
155(4):575-580.
PMID: 33210141
Objectives: Aberrant expression of neuroendocrine markers has been reported in angiosarcomas and can occasionally result in diagnostic confusion. The aim of this study was to evaluate the expression of insulinoma-associated...
17.
Maitituoheti M, Keung E, Tang M, Yan L, Alam H, Han G, et al.
Cell Rep
. 2020 Oct;
33(3):108293.
PMID: 33086062
Histone methyltransferase KMT2D harbors frequent loss-of-function somatic point mutations in several tumor types, including melanoma. Here, we identify KMT2D as a potent tumor suppressor in melanoma through an in vivo...
18.
Cho W, Wang W, Milton D, Ingram D, Nagarajan P, Curry J, et al.
Arch Pathol Lab Med
. 2020 Oct;
145(7):842-850.
PMID: 33053175
Context.—: Molecularly distinct from cutaneous melanomas arising from sun-exposed sites, acral lentiginous melanomas (ALMs) typically lack ultraviolet-signature mutations, such as telomerase reverse transcriptase (TERT) promoter mutations. Instead, ALMs show a...
19.
Panse G, Mito J, Ingram D, Wani K, Khan S, Lazar A, et al.
Histopathology
. 2020 Aug;
78(2):321-326.
PMID: 32735735
Background And Aims: Complete loss of histone H3 lysine 27 trimethylation (H3K27me3) has recently emerged as a biomarker for malignant peripheral nerve sheath tumours (MPNST). Loss of H3K27me3 staining has...
20.
Chrisinger J, Al-Zaid T, Keung E, Leung C, Lin H, Roland C, et al.
J Surg Oncol
. 2019 Jun;
120(3):382-388.
PMID: 31206726
Background And Objectives: Well-differentiated liposarcomas (WDL) are often partly composed of sclerotic tissue, however, the amount varies widely between tumors, and its prognostic significance is unknown. We hypothesized that tumors...