Davide Castaldi
Overview
Explore the profile of Davide Castaldi including associated specialties, affiliations and a list of published articles.
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12
Citations
217
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Recent Articles
1.
Pereira M, Finazzi V, Rizzuti L, Aprile D, Aiello V, Mollica L, et al.
Mol Psychiatry
. 2025 Feb;
PMID: 39987231
Germline mutations of YY1 cause Gabriele-de Vries syndrome (GADEVS), a neurodevelopmental disorder featuring intellectual disability and a wide range of systemic manifestations. To dissect the cellular and molecular mechanisms underlying...
2.
Caporale N, Castaldi D, Rigoli M, Cheroni C, Valenti A, Stucchi S, et al.
Nat Methods
. 2024 Dec;
22(2):358-370.
PMID: 39653820
Dissecting human neurobiology at high resolution and with mechanistic precision requires a major leap in scalability, given the need for experimental designs that include multiple individuals and, prospectively, population cohorts....
3.
Bosone C, Castaldi D, Burkard T, Guzman S, Wyatt T, Cheroni C, et al.
Nat Methods
. 2024 Sep;
21(11):2147-2159.
PMID: 39294368
Organoids generating major cortical cell types in distinct compartments are used to study cortical development, evolution and disorders. However, the lack of morphogen gradients imparting cortical positional information and topography...
4.
Pereira M, Finazzi V, Rizzuti L, Aprile D, Aiello V, Mollica L, et al.
bioRxiv
. 2024 Feb;
PMID: 38405909
Germline mutations of YY1 cause Gabriele-de Vries syndrome (GADEVS), a neurodevelopmental disorder featuring intellectual disability and a wide range of systemic manifestations. To dissect the cellular and molecular mechanisms underlying...
5.
Manti P, Trattaro S, Castaldi D, Pezzali M, Spaggiari L, Testa G
Trends Mol Med
. 2021 Dec;
28(1):67-78.
PMID: 34865984
Thymic epithelial tumors (TETs) have been characterized at the molecular level through bioptic sections and cell lines. Despite these advances, there is a need for a more thorough characterization of...
6.
Aghemo A, Grassi E, Rumi M, DAmbrosio R, Galmozzi E, Degasperi E, et al.
PLoS One
. 2014 Apr;
9(4):e95881.
PMID: 24760000
Background: Severe anemia is a common side effect of Pegylated Interferon + Ribavirin (PR) and Telaprevir (TVR) in hepatitis C virus (HCV) genotype 1 patients with advanced fibrosis or cirrhosis...
7.
Vitale G, Brugts M, Ogliari G, Castaldi D, Fatti L, Varewijck A, et al.
Aging (Albany NY)
. 2012 Sep;
4(9):580-9.
PMID: 22983440
Unlabelled: Centenarians' offspring represent a suitable model to study age-dependent variables (e.g. IGF-I) potentially involved in the modulation of the lifespan. The aim of the present study was to investigate...
8.
Gentilini D, Mari D, Castaldi D, Remondini D, Ogliari G, Ostan R, et al.
Age (Dordr)
. 2012 Aug;
35(5):1961-73.
PMID: 22923132
The role of epigenetics in the modulation of longevity has not been studied in humans. To this aim, (1) we evaluated the DNA methylation from peripheral leukocytes of 21 female...
9.
Benigni A, Orisio S, Noris M, Iatropoulos P, Castaldi D, Kamide K, et al.
Age (Dordr)
. 2012 May;
35(3):993-1005.
PMID: 22569962
Longevity phenotype in humans results from the influence of environmental and genetic factors. Few gene polymorphisms have been identified so far with a modest effect on lifespan leaving room for...
10.
Meazza C, Vitale G, Pagani S, Castaldi D, Ogliari G, Mari D, et al.
J Pediatr Endocrinol Metab
. 2012 Feb;
24(11-12):953-7.
PMID: 22308847
Adipose tissue seems to be a pivotal organ in the aging process. We investigated whether healthy aging could have its roots in a sound metabolic condition from the first year...