David Yiu Leung Chan
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Explore the profile of David Yiu Leung Chan including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
140
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Recent Articles
1.
Xu M, Zhao M, Yang H, Liu M, Chan C, Fung K, et al.
Medicine (Baltimore)
. 2025 Feb;
104(6):e41501.
PMID: 39928763
The manual method of semen analysis is vital in andrology laboratories. To solve the labor-intensive, time-consuming, and subjective problem, computer-assisted sperm analysis (CASA) systems have been developed. However, it is...
2.
Jin J, Yim H, Chang H, Wang Y, Choy K, Chan S, et al.
PNAS Nexus
. 2024 Oct;
3(10):pgae419.
PMID: 39359400
Infertility is associated with the alteration of the seminal microbiome. However, the onset of dysbiosis remains controversial and the involvement of host factors remains elusive. This study investigates the alterations...
3.
Yang H, Chan D
Int J Biochem Cell Biol
. 2023 Jun;
161:106440.
PMID: 37336424
No abstract available.
4.
Testis cell pyroptosis mediated by CASP1 and CASP4: possible sertoli cell-only syndrome pathogenesis
Liu W, Li X, Ma Q, Zhu Y, Zhao W, Yang Y, et al.
Reprod Biol Endocrinol
. 2023 Jun;
21(1):53.
PMID: 37296437
Background: Sertoli cell-only syndrome (SCOS) is the most serious pathological type of non-obstructive azoospermia. Recently, several genes related to SCOS have been identified, including FANCM, TEX14, NR5A1, NANOS2, PLK4, WNK3,...
5.
Shi X, Ren M, Wang L, Chan C, Chan D, Quan S, et al.
J Trace Elem Med Biol
. 2023 May;
78:127196.
PMID: 37209528
Background: Previous epidemiology studies reported that heavy metal/metalloid exposure is associated with the impairment of semen quality. However, it is still not clear whether the in vitro fertilization (IVF)/intracytoplasmic sperm...
6.
Cong L, Wang S, Yeung S, Lee J, Chung J, Chan D
Int J Mol Sci
. 2023 Apr;
24(7).
PMID: 37047114
Ovarian dermoid cysts, also called mature cystic teratomas (MCTs), account for 69% of ovarian germ cell tumors in young women. The tumors are formed by tissues derived from three germ...
7.
Chan S, Wan C, Law T, Chan D, Fok E
Int J Mol Sci
. 2022 Dec;
23(24).
PMID: 36555356
Apart from the paternal half of the genetic material, the male gamete carries assorted epigenetic marks for optimal fertilization and the developmental trajectory for the early embryo. Recent works showed...
8.
Zhang F, Li W, Chu H, Luk A, Tsang S, Lee W, et al.
Genomics
. 2022 Dec;
114(3):110541.
PMID: 36528977
No abstract available.
9.
Dong Z, Qian J, Law T, Chau M, Cao Y, Xue S, et al.
Hum Genet
. 2022 Dec;
142(3):363-377.
PMID: 36526900
Currently, routine genetic investigation for male infertility includes karyotyping analysis and PCR for Y chromosomal microdeletions to provide prognostic information such as sperm retrieval success rate. However, over 85% of...
10.
Xu M, Wu W, Zhao M, Chung J, Li T, Chan D
Int J Biochem Cell Biol
. 2022 Sep;
152:106298.
PMID: 36122887
Amorphic or defected oocytes and embryos are commonly observed in assisted reproductive technology (ART) laboratories. It is believed that a proper gene expression at each stage of embryo development contributes...