David Wille
Overview
Explore the profile of David Wille including associated specialties, affiliations and a list of published articles.
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13
Citations
296
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0
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Recent Articles
1.
Jones N, Nathanson A, Chell S, DeAngelis E, Whelan G, Wille D, et al.
Int J Dev Neurosci
. 2022 Jun;
82(5):423-435.
PMID: 35662244
Hypoxic-ischemic encephalopathy (HIE) in newborns is associated with high morbidity and mortality, with many babies suffering long-term neurological deficits. Currently, treatment options are limited to therapeutic hypothermia, which is not...
2.
Soskic B, Cano-Gamez E, Smyth D, Ambridge K, Ke Z, Matte J, et al.
Nat Genet
. 2022 May;
54(6):817-826.
PMID: 35618845
During activation, T cells undergo extensive gene expression changes that shape the properties of cells to exert their effector function. Understanding the regulation of this process could help explain how...
3.
Vonzun L, Gonser M, Moehrlen U, Mazzone L, Meuli M, Kandler L, et al.
Ultraschall Med
. 2022 Feb;
44(1):68-74.
PMID: 35135034
Background: Increased pulse wave reflection in the fetal arterial system, illustrated by a second systolic peak (M-sign) in middle cerebral artery (MCA) Doppler waveforms, allows interpretation of fetal systemic vasoconstriction....
4.
Vonzun L, Kahr M, Wille D, Kottke R, Moehrlen U, Meuli M, et al.
Ultraschall Med
. 2020 Oct;
43(2):181-185.
PMID: 33007788
Purpose: The goal of this study was to assess the accuracy of prenatal anatomical level determination by ultrasound (US) and magnetic resonance imaging (MRI) by analyzing the congruence with the...
5.
Cano-Gamez E, Soskic B, Roumeliotis T, So E, Smyth D, Baldrighi M, et al.
Nat Commun
. 2020 Apr;
11(1):1801.
PMID: 32286271
Naïve CD4 T cells coordinate the immune response by acquiring an effector phenotype in response to cytokines. However, the cytokine responses in memory T cells remain largely understudied. Here we...
6.
Soskic B, Cano-Gamez E, Smyth D, Rowan W, Nakic N, Esparza-Gordillo J, et al.
Nat Genet
. 2019 Sep;
51(10):1486-1493.
PMID: 31548716
Immune-disease-associated variants are enriched in active chromatin regions of T cells and macrophages. However, whether these variants function in specific cell states is unknown. Here we stimulated T cells and...
7.
Mohrlen U, Ochsenbein-Kolble N, Mazzone L, Kraehenmann F, Husler M, Casanova B, et al.
Fetal Diagn Ther
. 2019 Jun;
47(2):91-97.
PMID: 31167195
Introduction: The Management of Myelomeningocele Study, a.k.a. the MOMS trial, was published in 2011 in the New England Journal of Medicine. This prospective randomized controlled trial proved to be a...
8.
Hackenberg A, Baumer A, Sticht H, Schmitt B, Kroell-Seger J, Wille D, et al.
Neuropediatrics
. 2014 Apr;
45(4):261-4.
PMID: 24710820
Mutations of the SCN2A gene have originally been described in association with benign familial neonatal-infantile seizures (BFNIS). Recently, single patients with more severe phenotypes and persisting epileptic encephalopathies have been...
9.
Toelle S, Wille D, Schmitt B, Scheer I, Thony B, Plecko B
Epileptic Disord
. 2014 Feb;
16(1):88-92.
PMID: 24556562
Loss-of-function mutations in the FOLR1 gene (MIM *136430), encoding the folate receptor alpha, impair cerebral folate transport and lead to a progressive neurometabolic disorder. We report on a 5-year-old boy...
10.
Teo J, Bentley G, Lawrence P, Soltesz F, Miller S, Wille D, et al.
Int J Neuropsychopharmacol
. 2014 Jan;
17(5):705-13.
PMID: 24405657
The brain-derived neurotropic factor (BDNF) Val66Met polymorphism has been associated with abnormalities of synaptic plasticity in animal models, and abnormalities in motor cortical plasticity have also been described in humans...