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David W Williams

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Articles 91
Citations 2111
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Recent Articles
1.
Twigg J, Smith A, Haury C, Wilson M, Lees J, Waters M, et al.
J Med Microbiol . 2023 Jun; 72(6). PMID: 37341468
Bacterial pneumonia is a common cause of morbidity and mortality in elderly individuals. While the incidence of edentulism is falling, approximately 19 % of the UK population wear a full...
2.
Vanhatalo A, LHeureux J, Kelly J, Blackwell J, Wylie L, Fulford J, et al.
Redox Biol . 2021 Mar; 41:101933. PMID: 33721836
Many oral bacteria reduce inorganic nitrate, a natural part of a vegetable-rich diet, into nitrite that acts as a precursor to nitric oxide, a regulator of vascular tone and neurotransmission....
3.
Serra E, Saubade F, Ligorio C, Whitehead K, Sloan A, Williams D, et al.
Microorganisms . 2020 Feb; 8(2). PMID: 32041100
spp. are the most prevalent fungi of the human microbiota and are opportunistic pathogens that can cause oral candidiasis. Management of such infections is limited due to the low number...
4.
Morse D, Smith A, Wilson M, Marsh L, White L, Posso R, et al.
Sci Rep . 2019 Jul; 9(1):10228. PMID: 31308427
Denture-associated stomatitis (DS) affects over two-thirds of denture-wearers. DS presents as erythema of the palatal mucosa in areas where denture-surface associated polymicrobial biofilms containing the fungus Candida albicans exist. The...
5.
Vanhatalo A, Blackwell J, LHeureux J, Williams D, Smith A, van der Giezen M, et al.
Free Radic Biol Med . 2018 May; 124:21-30. PMID: 29807159
Imbalances in the oral microbial community have been associated with reduced cardiovascular and metabolic health. A possible mechanism linking the oral microbiota to health is the nitrate (NO)-nitrite (NO)-nitric oxide...
6.
Morse D, Wilson M, Wei X, A O Lewis M, Bradshaw D, Murdoch C, et al.
J Med Microbiol . 2018 Feb; 67(3):364-375. PMID: 29458673
Purpose: In vitro analyses of virulence, pathogenicity and associated host cell responses are important components in the study of biofilm infections. The Candida-related infection, denture-associated oral candidosis, affects up to...
7.
Das L, Liu E, Saeed A, Williams D, Hu H, Li C, et al.
Bioresour Technol . 2017 Aug; 244(Pt 1):641-649. PMID: 28810219
This study takes combined field trial, lab experiment, and economic analysis approaches to evaluate the potential of industrial hemp in comparison with kenaf, switchgrass and biomass sorghum. Agronomy data suggest...
8.
Marino P, Wise M, Smith A, Marchesi J, Riggio M, A O Lewis M, et al.
J Crit Care . 2017 Mar; 39:149-155. PMID: 28259058
Purpose: Mechanically ventilated patients are at risk for developing ventilator-associated pneumonia, and it has been reported that dental plaque provides a reservoir of respiratory pathogens that may aspirate to the...
9.
Mariyaselvam M, Marsh L, Bamford S, Smith A, Wise M, Williams D
BMC Anesthesiol . 2017 Mar; 17(1):36. PMID: 28257624
Background: Aspiration of subglottic secretions past the endotracheal tube (ETT) cuff is a prerequisite for developing ventilator-associated pneumonia (VAP). Subglottic secretion drainage (SSD) ETTs reduce aspiration of subglottic secretions and...
10.
Marino P, Hannigan A, Haywood S, Cole J, Palmer N, Emanuel C, et al.
BMJ Open Respir Res . 2016 Nov; 3(1):e000150. PMID: 27843549
Introduction: During critical illness, dental plaque may serve as a reservoir of respiratory pathogens. This study compared the effectiveness of toothbrushing with a small-headed toothbrush or a foam-headed swab in...