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David W Farnsworth

Explore the profile of David W Farnsworth including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
DeLaitsch A, Pridgen J, Tytla A, Peach M, Hu R, Farnsworth D, et al.
J Am Chem Soc . 2022 Mar; 144(11):4925-4941. PMID: 35282679
Germline antibodies, the initial set of antibodies produced by the immune system, are critical for host defense, and information about their binding properties can be useful for designing vaccines, understanding...
2.
Morningstar M, Roth T, Farnsworth D, Smith M, Watson K, Buckheit Jr R, et al.
J Med Chem . 2007 Aug; 50(17):4003-15. PMID: 17663538
In an ongoing effort to develop novel and potent nonnucleoside HIV-1 reverse transcriptase (RT) inhibitors that are effective against the wild type (WT) virus and clinically observed mutants, 1,2-bis-substituted benzimidazoles...
3.
Smith M, Hose B, Hawkins A, Lipchock J, Farnsworth D, Rizzo R, et al.
J Med Chem . 2003 May; 46(10):1940-7. PMID: 12723956
The energies and physical descriptors for the binding of 20 novel 1-(2,6-difluorobenzyl)-2-(2,6-difluorophenyl)benzimidazole analogues (BPBIs) to HIV-1 reverse transcriptase (RT) have been determined using Monte Carlo (MC) simulations. The crystallographic structure...