David Tinaquero
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Explore the profile of David Tinaquero including associated specialties, affiliations and a list of published articles.
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6
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97
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Recent Articles
1.
Nieto-Marin P, Tinaquero D, Utrilla R, Cebrian J, Gonzalez-Guerra A, Crespo-Garcia T, et al.
Cardiovasc Res
. 2021 Feb;
118(4):1046-1060.
PMID: 33576403
Aims: The transcription factor Tbx5 controls cardiogenesis and drives Scn5a expression in mice. We have identified two variants in TBX5 encoding p. D111Y and p. F206L Tbx5, respectively, in two...
2.
Tinaquero D, Crespo-Garcia T, Utrilla R, Nieto-Marin P, Gonzalez-Guerra A, Rubio-Alarcon M, et al.
Sci Rep
. 2020 Jul;
10(1):10707.
PMID: 32612162
Synapse-Associated Protein 97 (SAP97) is an anchoring protein that in cardiomyocytes targets to the membrane and regulates Na and K channels. Here we compared the electrophysiological effects of native (WT)...
3.
Perez-Hernandez M, Matamoros M, Alfayate S, Nieto-Marin P, Utrilla R, Tinaquero D, et al.
JCI Insight
. 2018 Sep;
3(18).
PMID: 30232268
Cardiac Nav1.5 and Kir2.1-2.3 channels generate Na (INa) and inward rectifier K (IK1) currents, respectively. The functional INa and IK1 interplay is reinforced by the positive and reciprocal modulation between...
4.
Nieto-Marin P, Jimenez-Jaimez J, Tinaquero D, Alfayate S, Utrilla R, Del Mar Rodriguez Vazquez Del Rey M, et al.
Rev Esp Cardiol (Engl Ed)
. 2018 Apr;
72(4):324-332.
PMID: 29691127
Introduction And Objectives: A known long QT syndrome-related mutation in Nav1.5 cardiac channels (p.R1644H) was found in 4 members of a Spanish family but only 1 of them showed prolongation...
5.
Utrilla R, Nieto-Marin P, Alfayate S, Tinaquero D, Matamoros M, Perez-Hernandez M, et al.
Front Physiol
. 2017 Nov;
8:903.
PMID: 29184507
Cardiac Kir2.1 and Nav1.5 channels generate the inward rectifier K (I) and the Na (I) currents, respectively. There is a mutual interplay between the ventricular I and I densities, because...
6.
Caballero R, Utrilla R, Amoros I, Matamoros M, Perez-Hernandez M, Tinaquero D, et al.
Proc Natl Acad Sci U S A
. 2017 Jan;
114(3):E416-E425.
PMID: 28049825
Long QT syndrome (LQTS) exhibits great phenotype variability among family members carrying the same mutation, which can be partially attributed to genetic factors. We functionally analyzed the KCNH2 (encoding for...