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David Tabatadze

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Recent Articles
1.
Le Hars M, Castro-Vega L, Rajabi F, Tabatadze D, Romero M, Pinskaya M, et al.
Biol Direct . 2023 Jul; 18(1):38. PMID: 37434219
Background: Prostate cancer remains one of the deadliest neoplasms in developed countries. Identification of new molecular markers that predict the onset and progression of the disease could improve its clinical...
2.
Metelev V, Zhang S, Tabatadze D, Kumar A, Bogdanov Jr A
Mol Biosyst . 2013 Aug; 9(10):2447-53. PMID: 23925269
We report a general phenomenon of the formation of either a fluorescent or an entirely quenched oligodeoxynucleotide (ODN) duplex system by hybridizing pairs of complementary ODNs with identical chemical composition....
3.
Metelev V, Zhang S, Tabatadze D, Bogdanov A
Bioconjug Chem . 2011 Mar; 22(4):759-65. PMID: 21417216
Three oligodeoxyribonucleotides (ODN) covalently labeled with near-infrared (NIR) fluorochromes were synthesized and characterized with a goal of comparing in vitro a hairpin-based and a duplex-based FRET probe designed for the...
4.
Zelickson B, Walgrave S, Al-Arashi M, Yaroslavsky I, Altshuler G, Childs J, et al.
Lasers Surg Med . 2011 Mar; 43(2):137-42. PMID: 21384395
Background And Objective: Non-ablative fractional lasers have been used in skin rejuvenation procedures with some success. In general, the optimum area coverage and depths of the fractional thermal injury zones...
5.
Zhang S, Metelev V, Tabatadze D, Zamecnik P, Bogdanov Jr A
Oligonucleotides . 2008 Aug; 18(3):235-43. PMID: 18699740
Two types of reporters for optical sensing of NF-kappaB p50 protein-oligodeoxyribonucleotide (ODN) duplex interactions were designed and compared in vitro. The reporters were based on the effect of fluorescence resonance...
6.
Zhang S, Metelev V, Tabatadze D, Zamecnik P, Bogdanov Jr A
Proc Natl Acad Sci U S A . 2008 Mar; 105(11):4156-61. PMID: 18337505
Optical imaging in the near-infrared (NIR) range enables detecting ligand-receptor interactions and enzymatic activity in vivo due to lower scattering and absorption of NIR photons in the tissue. We designed...
7.
Dierickx C, Khatri K, Tannous Z, Childs J, Cohen R, Erofeev A, et al.
Lasers Surg Med . 2008 Feb; 40(2):113-23. PMID: 18306165
Background And Objectives: Fractional ablation offers the potential benefits of full-surface ablative skin resurfacing while minimizing adverse effects. The purpose of this study was to evaluate the safety, damage profile,...
8.
Tabatadze D, Zamecnik P, Yanachkov I, Wright G, Pierson K, Zhang S, et al.
Nucleosides Nucleotides Nucleic Acids . 2008 Jan; 27(2):157-72. PMID: 18205070
A novel thymidine phosphoramidite synthon was synthesized and successfully used for incorporation of primary amino groups, attached through a triethylene glycol linker to the internucleoside phosphates, at desired locations during...
9.
Harth G, Zamecnik P, Tabatadze D, Pierson K, Horwitz M
Proc Natl Acad Sci U S A . 2007 Apr; 104(17):7199-204. PMID: 17438292
We have investigated the efficacy of modifying gene-specific antisense phosphorothioate oligodeoxyribonucleotides (PS-ODNs) by the addition of 5' and 3' hairpin extensions. As a model system, we have targeted the Mycobacterium...
10.
Harth G, Horwitz M, Tabatadze D, Zamecnik P
Proc Natl Acad Sci U S A . 2002 Nov; 99(24):15614-9. PMID: 12427974
We have investigated the effect of sequence-specific antisense phosphorothioate-modified oligodeoxyribonucleotides (PS-ODNs) targeting different regions of each of the 3032-kDa protein complex (antigen 85 complex) encoding genes on the multiplication of...