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David T Pruitt

Explore the profile of David T Pruitt including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 268
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Recent Articles
1.
Carroll A, Pruitt D, Riley J, Danaphongse T, Rennaker R, Engineer C, et al.
Sci Rep . 2024 Aug; 14(1):18955. PMID: 39147873
Learning new skills requires neuroplasticity. Vagus nerve stimulation (VNS) during sensory and motor events can increase neuroplasticity in networks related to these events and might therefore serve to facilitate learning...
2.
Epperson J, Meyers E, Pruitt D, Wright J, Hudson R, Adehunoluwa E, et al.
Neurorehabil Neural Repair . 2024 May; 38(7):493-505. PMID: 38712875
Background: Recent evidence demonstrates that manually triggered vagus nerve stimulation (VNS) combined with rehabilitation leads to increased recovery of upper limb motor function after stroke. This approach is premised on...
3.
Ruiz A, Malley K, Danaphongse T, Ahmad F, Beltran C, White M, et al.
Neuroscience . 2023 Oct; 532:79-86. PMID: 37778688
Chronic sensory loss is a common and undertreated consequence of many forms of neurological injury. Emerging evidence indicates that vagus nerve stimulation (VNS) delivered during tactile rehabilitation promotes recovery of...
4.
Pruitt D, Duong-Nguyen Y, Meyers E, Epperson J, Wright J, Hudson R, et al.
Games Health J . 2022 Nov; 12(1):73-85. PMID: 36318505
Stroke is a leading cause of chronic motor disability. While physical rehabilitation can promote functional recovery, several barriers prevent patients from receiving optimal rehabilitative care. Easy access to at-home rehabilitative...
5.
Pruitt D, Danaphongse T, Lutchman M, Patel N, Reddy P, Wang V, et al.
Transl Stroke Res . 2020 Jun; 12(1):65-71. PMID: 32583333
Vagus nerve stimulation (VNS) paired with rehabilitative training enhances recovery of function in models of stroke and is currently under investigation for use in chronic stroke patients. Dosing is critical...
6.
Morrison R, Danaphongse T, Pruitt D, Adcock K, Mathew J, Abe S, et al.
Behav Brain Res . 2020 Jun; 391:112705. PMID: 32473844
Pairing vagus nerve stimulation (VNS) with rehabilitation has emerged as a potential strategy to improve recovery after neurological injury, an effect ascribed to VNS-dependent enhancement of synaptic plasticity. Previous studies...
7.
Souza R, Robertson N, Mathew E, Tabet M, Bucksot J, Pruitt D, et al.
Prog Neuropsychopharmacol Biol Psychiatry . 2019 Dec; 99:109848. PMID: 31863872
Vagus nerve stimulation (VNS) has shown promise as an adjuvant treatment for posttraumatic stress disorder (PTSD), as it enhances fear extinction and reduces anxiety symptoms in multiple rat models of...
8.
Souza R, Robertson N, Pruitt D, Gonzales P, Hays S, Rennaker R, et al.
Stress . 2019 Apr; 22(4):509-520. PMID: 31010369
We have shown that vagus nerve stimulation (VNS) enhances extinction of conditioned fear and reduces anxiety in rat models of PTSD using moderate stress. However, it is still unclear if...
9.
Ganzer P, Darrow M, Meyers E, Solorzano B, Ruiz A, Robertson N, et al.
Elife . 2018 Mar; 7. PMID: 29533186
Recovery from serious neurological injury requires substantial rewiring of neural circuits. Precisely-timed electrical stimulation could be used to restore corrective feedback mechanisms and promote adaptive plasticity after neurological insult, such...
10.
Souza R, Robertson N, Pruitt D, Noble L, Meyers E, Gonzales P, et al.
J Neurosci Methods . 2018 Feb; 298:54-65. PMID: 29452180
Background: Fear conditioning (FC) in rodents is the most used animal model to investigate the neurobiology of posttraumatic stress disorder (PTSD). Although research using FC has generated a better understanding...