David Serreze
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Explore the profile of David Serreze including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
208
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0
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Recent Articles
1.
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes
Funsten M, Yurkovetskiy L, Kuznetsov A, Reiman D, Hansen C, Senter K, et al.
Cell Host Microbe
. 2023 Jan;
31(2):213-227.e9.
PMID: 36603588
Diet and commensals can affect the development of autoimmune diseases like type 1 diabetes (T1D). However, whether dietary interventions are microbe-mediated was unclear. We found that a diet based on...
2.
De Groot A, Skowron G, White J, Boyle C, Richard G, Serreze D, et al.
Sci Rep
. 2019 Nov;
9(1):16103.
PMID: 31695065
Type 1 Diabetes (T1D) is an autoimmune disease that is associated with effector T cell (Teff) destruction of insulin-producing pancreatic beta-islet cells. Among the therapies being evaluated for T1D is...
3.
Egia-Mendikute L, Arpa B, Rosell-Mases E, Corral-Pujol M, Carrascal J, Carrillo J, et al.
Front Immunol
. 2019 Aug;
10:1732.
PMID: 31428087
Previous studies indicate that B-lymphocytes play a key role activating diabetogenic T-lymphocytes during the development of autoimmune diabetes. Recently, two transgenic NOD mouse models were generated: the NOD- and the...
4.
Scheuplein F, Lamont D, Poynter M, Boyson J, Serreze D, Lundblad L, et al.
PLoS One
. 2015 Oct;
10(10):e0140729.
PMID: 26474487
Invariant Natural Killer T (iNKT) cells are a T cell subset expressing an invariant T Cell Receptor (TCR) that recognizes glycolipid antigens rather than peptides. The cells have both innate-like...
5.
Presa M, Ortiz A, Garabatos N, Izquierdo C, Rivas E, Teyton L, et al.
Eur J Immunol
. 2013 Aug;
43(11):2969-79.
PMID: 23925934
The cholera toxin B subunit (CTB) has been used as adjuvant to improve oral vaccine delivery in type 1 diabetes. The effect of CTB/peptide formulations on Ag-specific CD4(+) T cells...
6.
Wekerle H, Flugel A, Fugger L, Schett G, Serreze D
Nat Med
. 2012 Jan;
18(1):66-70.
PMID: 22227675
No abstract available.
7.
Razavi R, Chan Y, Afifiyan F, Liu X, Wan X, Yantha J, et al.
Cell
. 2006 Dec;
127(6):1123-35.
PMID: 17174891
In type 1 diabetes, T cell-mediated death of pancreatic beta cells produces insulin deficiency. However, what attracts or restricts broadly autoreactive lymphocyte pools to the pancreas remains unclear. We report...
8.
Bonifacio E, Atkinson M, Eisenbarth G, Serreze D, Kay T, Lee-Chan E, et al.
Ann N Y Acad Sci
. 2002 May;
958:1-2.
PMID: 12021078
The aim of this workshop was to identify autoantibody assays that could provide useful markers of autoimmunity in the NOD mouse model for type 1 diabetes. It was demonstrated that...