David Schley
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Explore the profile of David Schley including associated specialties, affiliations and a list of published articles.
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17
Citations
120
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Recent Articles
1.
Ellis J, Brown E, Colenutt C, Schley D, Gubbins S
Epidemics
. 2024 Jan;
46:100740.
PMID: 38232411
To control an outbreak of an infectious disease it is essential to understand the different routes of transmission and how they contribute to the overall spread of the pathogen. With...
2.
Giorgakoudi K, Schley D, Juleff N, Gubbins S, Ward J
Math Biosci
. 2023 Jul;
363:109052.
PMID: 37495013
Type I interferons (IFN) are the first line of immune response against infection. In this study, we explore the interaction between Type I IFN and foot-and-mouth disease virus (FMDV), focusing...
3.
Hegazy Y, Schley D, Ridler A, Beauvais W, Musallam I, Guitian J
Transbound Emerg Dis
. 2020 Oct;
68(4):2364-2375.
PMID: 33118284
Small ruminant brucellosis remains endemic in many low- and middle-income countries (LMICs), where it poses a major economic and public health burden. Lack of resources to support long-term vaccination, inherent...
4.
Giorgakoudi K, Gubbins S, Ward J, Juleff N, Zhang Z, Schley D
PLoS One
. 2015 Oct;
10(10):e0138571.
PMID: 26431527
Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals. FMD virus (FMDV) shows a strong tropism for epithelial cells, and FMD is characterised by cell lysis and the...
5.
Goodwin R, Schley D, Lai K, Ceddia G, Barnett J, Cook N
Infect Dis Rep
. 2014 Jan;
4(2):e37.
PMID: 24470951
Zoonotic infections are on the increase worldwide, but most research into the biological, environmental and life science aspects of these infections has been conducted in separation. In this review we...
6.
Schley D, Whittaker R, Neuman B
J R Soc Interface
. 2013 Jul;
10(86):20130403.
PMID: 23864502
Viral replication occurs within cells, with release (and onward infection) primarily achieved through two alternative mechanisms: lysis, in which virions emerge as the infected cell dies and bursts open; or...
7.
Kleinlutzum D, Weaver G, Schley D
Res Vet Sci
. 2013 Jul;
95(2):425-9.
PMID: 23849647
The prevention, control and reduction of livestock diseases require a good understanding of how the underlying causative agents are transmitted. On livestock premises the rate of spread is strongly determined...
8.
Neuman B, Kiss G, Al-Mulla H, Dokland T, Buchmeier M, Weikl T, et al.
PLoS One
. 2013 Mar;
8(2):e57916.
PMID: 23469104
Enveloped virus release is driven by poorly understood proteins that are functional analogs of the coat protein assemblies that mediate intracellular vesicle trafficking. We used differential electron density mapping to...
9.
Schley D, Tanaka R, Leungchavaphongse K, Shahrezaei V, Ward J, Grant C, et al.
PLoS One
. 2012 Feb;
7(2):e30435.
PMID: 22363437
Foot and mouth disease virus causes a livestock disease of significant global socio-economic importance. Advances in its control and eradication depend critically on improvements in vaccine efficacy, which can be...
10.
Schley D, Whittle S, Taylor M, Kiss I
Prev Vet Med
. 2012 Feb;
106(2):174-84.
PMID: 22341734
Successful control of livestock diseases requires an understanding of how they spread amongst animals and between premises. Mathematical models can offer important insight into the dynamics of disease, especially when...