David S Chatelet
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Explore the profile of David S Chatelet including associated specialties, affiliations and a list of published articles.
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38
Citations
555
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Recent Articles
1.
Laundon D, Proudley E, Basford P, Katsamenis O, Chatelet D, Cleal J, et al.
Placenta
. 2024 Aug;
154:216-219.
PMID: 39096863
Placental structure is linked to function across morphological scales. In the placenta, changes to gross anatomy, such as surface area, volume, or blood vessel arrangement, are associated with suboptimal physiological...
2.
Pearson-Farr J, Doherty R, Chatelet D, Goggin P, Ng K, Lucas J, et al.
Reproduction
. 2023 Nov;
167(1).
PMID: 37999981
In Brief: The causes of subfertility and recurrent pregnancy loss are often unclear. This study shows that endometrial gland cilia from women with subfertility have ultrastructural defects. Abstract: Endometrial glands...
3.
Hartnell I, Woodhouse D, Jasper W, Mason L, Marwaha P, Graffeuil M, et al.
Brain
. 2023 Sep;
147(2):590-606.
PMID: 37703311
Frontotemporal lobar degeneration with tau (FTLD-tau) is a group of tauopathies that underlie ∼50% of FTLD cases. Identification of genetic risk variants related to innate/adaptive immunity have highlighted a role...
4.
Garland E, Dennett O, Lau L, Chatelet D, Bottlaender M, Nicoll J, et al.
J Neuroinflammation
. 2023 Aug;
20(1):186.
PMID: 37580767
The 18kD translocator protein (TSPO) is used as a positron emission tomography (PET) target to quantify neuroinflammation in patients. In Alzheimer's disease (AD), the cerebellum is the pseudo-reference region for...
5.
Laundon D, Katsamenis O, Thompson J, Goggin P, Chatelet D, Chavatte-Palmer P, et al.
Methods Cell Biol
. 2023 Jul;
177:241-267.
PMID: 37451769
Three-dimensional biological microscopy presents a trade-off between spatial resolution and field of view. Correlative approaches applying multiple imaging techniques to the same sample can therefore mitigate against these trade-offs. Here,...
6.
Noorani I, Sidlauskas K, Pellow S, Savage R, Norman J, Chatelet D, et al.
Brain Commun
. 2023 Jun;
5(3):fcad176.
PMID: 37324244
Glioblastoma is a devastating brain cancer for which effective treatments are required. Tumour-associated microglia and macrophages promote glioblastoma growth in an immune-suppressed microenvironment. Most recurrences occur at the invasive margin...
7.
Lewis R, Baskaran H, Green J, Tashev S, Palaiologou E, Lofthouse E, et al.
iScience
. 2022 Nov;
25(12):105453.
PMID: 36387021
The placental syncytiotrophoblast, a syncytium without cell-cell junctions, is the primary barrier between the mother and the fetus. Despite no apparent anatomical pathway for paracellular diffusion of solutes across the...
8.
Davies R, Griffiths C, Askelund K, Palaiologou E, Cleal J, Page A, et al.
Placenta
. 2022 May;
123:24-30.
PMID: 35533511
Introduction: Extracellular vesicles are now believed to be important mediators of placental-maternal communication. However, little is known about the formation of extracellular vesicles by human placenta. This study uses nanoscale...
9.
Tashev S, Parsons D, Hillman C, Harris S, Lofthouse E, Goggin P, et al.
Placenta
. 2021 Nov;
117:57-63.
PMID: 34768170
Introduction: The placental syncytiotrophoblast is the primary barrier between the mother and the fetus. To cross the placenta, nutrients and wastes must be transported across the apical microvillous and basal...
10.
Franco-Bocanegra D, Gourari Y, McAuley C, Chatelet D, Johnston D, Nicoll J, et al.
Sci Rep
. 2021 Aug;
11(1):15955.
PMID: 34354209
Microglia are the brain immune cells and their function is highly dependent on cell motility. It was hypothesised that morphological variability leads to differences in motility, ultimately impacting on the...