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David S Campo

Explore the profile of David S Campo including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 476
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Recent Articles
1.
Mosa A, Campo D, Khudyakov Y, AbouHaidar M, Gehring A, Zahoor A, et al.
Proc Natl Acad Sci U S A . 2023 Jun; 120(24):e2220294120. PMID: 37276424
A hepatitis C virus (HCV) vaccine is urgently needed. Vaccine development has been hindered by HCV's genetic diversity, particularly within the immunodominant hypervariable region 1 (HVR1). Here, we developed a...
2.
Campo D, Mosa A, Khudyakov Y
J Comput Biol . 2023 Jan; 30(4):420-431. PMID: 36602524
Application of genetic distances to measure phenotypic relatedness is a challenging task, reflecting the complex relationship between genotype and phenotype. Accurate assessment of proximity among sequences with different phenotypic traits...
3.
Talundzic E, Scott S, Owino S, Campo D, Lucchi N, Udhayakumar V, et al.
Pathogens . 2022 May; 11(5). PMID: 35631041
The protein VAR2CSA allows infected erythrocytes to accumulate within the placenta, inducing pathology and poor birth outcomes. Multiple exposures to placental malaria (PM) induce partial immunity against VAR2CSA, making it...
4.
Gussler J, Campo D, Dimitrova Z, Skums P, Khudyakov Y
BMC Bioinformatics . 2022 Feb; 23(1):62. PMID: 35135469
Background: Investigation of outbreaks to identify the primary case is crucial for the interruption and prevention of transmission of infectious diseases. These individuals may have a higher risk of participating...
5.
Campo D, Khudyakov Y
BMC Bioinformatics . 2020 Dec; 21(Suppl 18):482. PMID: 33375937
Background: In molecular epidemiology, comparison of intra-host viral variants among infected persons is frequently used for tracing transmissions in human population and detecting viral infection outbreaks. Application of Ultra-Deep Sequencing...
6.
Campo D, Gussler J, Sue A, Skums P, Khudyakov Y
PLoS One . 2020 Dec; 15(12):e0243622. PMID: 33284864
Persons who inject drugs (PWID) are at increased risk for overdose death (ODD), infections with HIV, hepatitis B (HBV) and hepatitis C virus (HCV), and noninfectious health conditions. Spatiotemporal identification...
7.
Campo D, Khudyakov Y
J Med Artif Intell . 2020 Jun; 3(7). PMID: 32478331
No abstract available.
8.
Campo D, Nayak V, Srinivasamoorthy G, Khudyakov Y
BMC Med Genomics . 2019 Jun; 12(Suppl 4):74. PMID: 31167647
Background: Ultra-Deep Sequencing (UDS) enabled identification of specific changes in human genome occurring in malignant tumors, with current approaches calling for the detection of specific mutations associated with certain cancers....
9.
Sims S, Longmire A, Campo D, Ramachandran S, Medrzycki M, Ganova-Raeva L, et al.
BMC Bioinformatics . 2018 Oct; 19(Suppl 11):358. PMID: 30343674
Background: Molecular surveillance and outbreak investigation are important for elimination of hepatitis C virus (HCV) infection in the United States. A web-based system, Global Hepatitis Outbreak and Surveillance Technology (GHOST),...
10.
Tsyvina V, Campo D, Sims S, Zelikovsky A, Khudyakov Y, Skums P
BMC Bioinformatics . 2018 Oct; 19(Suppl 11):360. PMID: 30343669
Background: Many biological analysis tasks require extraction of families of genetically similar sequences from large datasets produced by Next-generation Sequencing (NGS). Such tasks include detection of viral transmissions by analysis...