David R Sinacore
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Explore the profile of David R Sinacore including associated specialties, affiliations and a list of published articles.
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79
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3230
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Recent Articles
11.
Binder E, Christensen J, Stevens-Lapsley J, Bartley J, Berry S, Dobs A, et al.
Contemp Clin Trials
. 2021 Mar;
104:106356.
PMID: 33716173
Background: Up to 75% of hip fracture patients never recover to their pre-fracture functional status. Supervised exercise that includes strength training can improve functional recovery after hip fracture. The role...
12.
Bittel D, Bittel A, Varadhachary A, Pietka T, Sinacore D
Diabetes
. 2021 Feb;
70(5):1130-1144.
PMID: 33526590
Two-thirds of people with type 2 diabetes mellitus (T2DM) have or will develop chronic kidney disease (CKD), which is characterized by rapid renal decline that, together with superimposed T2DM-related metabolic...
13.
Bohnert K, Hastings M, Sinacore D, Johnson J, Klein S, McCormick J, et al.
Foot Ankle Int
. 2020 Feb;
41(5):536-548.
PMID: 32059624
Background: Decreased lean muscle mass in the lower extremity in diabetic peripheral neuropathy (DPN) is thought to contribute to altered joint loading, immobility, and disability. However, the mechanism behind this...
14.
Sinacore D, Smith K, Bohnert K, Gutekunst D, Johnson J, Strube M
JBMR Plus
. 2019 Dec;
3(12):e10243.
PMID: 31844830
Metatarsals are frequent sites of stress and fragility fractures in younger athletic populations and aging older adults. Metatarsal fractures are particularly common in Charcot neuroarthropathy (CN), a complication of diabetes...
15.
Tuttle L, Bittel D, Bittel A, Sinacore D
Can J Diabetes
. 2018 Mar;
42(5):478-483.
PMID: 29567079
Objectives: Diabesity (obesity and diabetes mellitus) has been identified as a potential contributor to early-onset frailty. Impairments contributing to early onset of physical frailty in this population are not well...
16.
Pritchard N, Smoliga J, Nguyen A, Branscomb M, Sinacore D, Taylor J, et al.
J Foot Ankle Res
. 2017 Dec;
10:52.
PMID: 29209416
Background: Metatarsal fractures, especially of the fifth metatarsal, are common injuries of the foot in a young athletic population, but the risk factors for this injury are not well understood....
17.
Sinacore D, Hastings M, Bohnert K, Strube M, Gutekunst D, Johnson J
Bone
. 2017 Sep;
105:237-244.
PMID: 28942120
Background: Neuropathic foot impairments treated with immobilization and off-loading result in osteolysis. In order to prescribe and optimize rehabilitation programs after immobilization we need to understand the magnitude of pedal...
18.
Commean P, Smith K, Hildebolt C, Bohnert K, Sinacore D, Prior F
J Clin Densitom
. 2017 Jul;
21(4):485-492.
PMID: 28668579
Inflammation-mediated foot osteopenia may play a pivotal role in the etiogenesis, pathogenesis, and therapeutic outcomes in individuals with diabetes mellitus (DM), peripheral neuropathy (PN), and Charcot neuroarthropathy (CN). Our objective...
19.
Villareal D, Aguirre L, Gurney A, Waters D, Sinacore D, Colombo E, et al.
N Engl J Med
. 2017 May;
376(20):1943-1955.
PMID: 28514618
Background: Obesity causes frailty in older adults; however, weight loss might accelerate age-related loss of muscle and bone mass and resultant sarcopenia and osteopenia. Methods: In this clinical trial involving...
20.
Sinacore D, Bohnert K, Smith K, Hastings M, Commean P, Gutekunst D, et al.
J Diabetes Complications
. 2017 Mar;
31(6):1014-1020.
PMID: 28254346
Aims: To determine local and systemic markers of inflammation and bone mineral density (BMD) in the foot and central sites in participants with diabetes mellitus and peripheral neuropathy (DMPN) with...