David R Goodlett
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Explore the profile of David R Goodlett including associated specialties, affiliations and a list of published articles.
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269
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8472
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Recent Articles
11.
Hofstaedter C, Chandler C, Met C, Gillespie J, Harro J, Goodlett D, et al.
mBio
. 2023 Dec;
15(2):e0282323.
PMID: 38131669
can survive in a myriad of environments, partially due to modifications of its lipid A, the membrane anchor of lipopolysaccharide. We previously demonstrated that divergent late acyltransferase paralogs, HtrB1 and...
12.
Mohammed Y, Tran K, Carlsten C, Ryerson C, Wong A, Lee T, et al.
J Proteome Res
. 2023 Dec;
23(1):52-70.
PMID: 38048423
Many COVID-19 survivors have post-COVID-19 conditions, and females are at a higher risk. We sought to determine (1) how protein levels change from acute to post-COVID-19 conditions, (2) whether females...
13.
Mikhael A, Hardie D, Smith D, Petrosova H, Ernst R, Goodlett D
Anal Chem
. 2023 Nov;
95(46):16796-16800.
PMID: 37943784
Lipopolysaccharides (LPSs) are a hallmark virulence factor of Gram-negative bacteria. They are complex, structurally heterogeneous mixtures due to variations in number, type, and position of their simplest units: fatty acids...
14.
Houston S, Gomez A, Geppert A, Eshghi A, Smith D, Waugh S, et al.
Sci Rep
. 2023 Oct;
13(1):18259.
PMID: 37880309
Comprehensive proteome-wide analysis of the syphilis spirochete, Treponema pallidum ssp. pallidum, is technically challenging due to high sample complexity, difficulties with obtaining sufficient quantities of bacteria for analysis, and the...
15.
Haq S, Oyler B, Williams E, Khan M, Goodlett D, Bachvaroff T, et al.
Mar Drugs
. 2023 Aug;
21(8).
PMID: 37623706
Dinoflagellates are unicellular organisms that are implicated in harmful algal blooms (HABs) caused by potent toxins that are produced through polyketide synthase (PKS) pathways. However, the exact mechanisms of toxin...
16.
MacPherson S, Duncan K, Goodlett D, Lum J
Curr Opin Biotechnol
. 2023 Aug;
83:102991.
PMID: 37619527
Despite practical complexities, isotope tracing studies in humans are becoming increasingly feasible. However, several technological challenges need to be addressed in order to take full advantage of human tracing studies....
17.
Mikhael A, Hardie D, Smith D, Petrosova H, Ernst R, Goodlett D
bioRxiv
. 2023 Jul;
PMID: 37461651
Lipopolysaccharide (LPS) is a hallmark virulence factor of Gram-negative bacteria. It is a complex, structurally heterogeneous mixture due to variations in number, type, and position of its simplest units: fatty...
18.
Petrosova H, Mikhael A, Culos S, Giraud-Gatineau A, Gomez A, Sherman M, et al.
Front Microbiol
. 2023 Jun;
14:1181034.
PMID: 37303810
Lipid A is the hydrophobic component of bacterial lipopolysaccharide and an activator of the host immune system. Bacteria modify their lipid A structure to adapt to the surrounding environment and,...
19.
Yang H, Sherman M, Koo C, Treaster L, Smith J, Gallaher S, et al.
J Am Soc Mass Spectrom
. 2023 May;
34(6):1047-1055.
PMID: 37184080
FLAT is a tandem mass spectrometric technique that can be used to rapidly generate spectral information applicable for structural elucidation of lipids like lipid A from Gram-negative bacterial species from...
20.
Eshghi A, Xie X, Hardie D, Chen M, Izaguirre F, Newman R, et al.
J Proteome Res
. 2023 Apr;
22(6):1589-1602.
PMID: 37093777
We compared three cell isolation and two proteomic sample preparation methods for single-cell and near-single-cell analysis. Whole blood was used to quantify hemoglobin (Hb) and glycated-Hb (gly-Hb) in erythrocytes using...