David R Geter
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Explore the profile of David R Geter including associated specialties, affiliations and a list of published articles.
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21
Citations
139
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Recent Articles
1.
Schapaugh A, McFadden L, Zorrilla L, Geter D, Stuchal L, Sunger N, et al.
Regul Toxicol Pharmacol
. 2015 Jun;
72(3):552-61.
PMID: 26044367
EPA's Endocrine Disruptor Screening Program Tier 1 battery consists of eleven assays intended to identify the potential of a chemical to interact with the estrogen, androgen, thyroid, or steroidogenesis systems....
2.
Oshida K, Vasani N, Jones C, Moore T, Hester S, Nesnow S, et al.
Nucl Recept Signal
. 2015 May;
13:e002.
PMID: 25949234
The nuclear receptor family member constitutive activated receptor (CAR) is activated by structurally diverse drugs and environmentally-relevant chemicals leading to transcriptional regulation of genes involved in xenobiotic metabolism and transport....
3.
Borgert C, Stuchal L, Mihaich E, Becker R, Bentley K, Brausch J, et al.
Birth Defects Res B Dev Reprod Toxicol
. 2014 Feb;
101(1):90-113.
PMID: 24510745
Weight of evidence (WoE) approaches are recommended for interpreting various toxicological data, but few systematic and transparent procedures exist. A hypothesis-based WoE framework was recently published focusing on the U.S....
4.
Geter D, Bhat V, Gollapudi B, Sura R, Hester S
Toxicol Sci
. 2014 Jan;
138(2):425-45.
PMID: 24449422
Low-dose extrapolation and dose-related transitions are paramount in the ongoing debate regarding the quantification of cancer risks for nongenotoxic carcinogens. Phenobarbital (PB) is a prototypical nongenotoxic carcinogen that activates the...
5.
Geter D, Ward W, Knapp G, DeAngelo A, Rubis J, Owen R, et al.
Transl Oncogenomics
. 2013 May;
1:33-52.
PMID: 23662038
Background: Potassium bromate (KBrO3), used in both the food and cosmetics industry, and a drinking water disinfection by-product, is a nephrotoxic compound and rodent carcinogen. To gain insight into the...
6.
LeBaron M, Geter D, Rasoulpour R, Gollapudi B, Thomas J, Murray J, et al.
Toxicol Appl Pharmacol
. 2013 Apr;
270(2):164-73.
PMID: 23607986
Registration of new plant protection products (e.g., herbicide, insecticide, or fungicide) requires comprehensive mammalian toxicity evaluation including carcinogenicity studies in two species. The outcome of the carcinogenicity testing has a...
7.
Jeong Y, Zhang F, Geter D, Wood A, Schisler M, Gollapudi B, et al.
Toxicol Lett
. 2012 Sep;
214(2):226-33.
PMID: 22940193
Adenosine deaminases (ADA) are key enzymes that deaminate adenosine (A) or deoxyadenosine (dA) and produce inosine or deoxyinosine (dI), respectively. While ADA only deaminates free dA, reactive nitrogen species (RNS)...
8.
Geter D, Zhang F, Schisler M, Wood A, Kan H, Jeong Y, et al.
Toxicol Mech Methods
. 2012 May;
22(7):547-54.
PMID: 22564015
Depletion of glutathione (GSH) in cells exposed to certain xenobiotics has been proposed to result in oxidative stress, which could lead to damage of cellular macromolecules such as proteins, lipids,...
9.
Delker D, Geter D, Roop B, Ward W, Ahlborn G, Allen J, et al.
J Biochem Mol Toxicol
. 2009 Dec;
23(6):406-18.
PMID: 20024957
We have previously observed that a chronic drinking water exposure to monomethylarsonous acid [MMA(III)], a cellular metabolite of inorganic arsenic, increases tumor frequency in the skin of keratin VI/ornithine decarboxylase...
10.
Geter D, Kan H, Lowe E, Rick D, Charles G, Gollapudi B, et al.
Toxicol Mech Methods
. 2009 Dec;
18(1):17-23.
PMID: 20020887
ABSTRACT Chlorpyrifos (CPF) is a widely used organophosphate insecticide. In addition to its known properties of cholinesterase inhibition, the production of reactive oxygen species (ROS) has been suggested as a...