David Polak
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Explore the profile of David Polak including associated specialties, affiliations and a list of published articles.
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54
Citations
902
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Recent Articles
1.
Cohen A, Avraham Verkauf T, Casap N, Chackartchi T, Polak D
Arch Oral Biol
. 2024 Nov;
170:106123.
PMID: 39561521
Objectives: Controlled long-term delivery of recombinant human bone morphogenic protein 2 (rhBMP2) eluted in a collagen scaffolds suffer from only a high initial burst release. The purpose of the current...
2.
Davidovich E, Sarne H, Shmueli A, Polak D
Clin Oral Investig
. 2024 Oct;
28(10):564.
PMID: 39358612
Objective: This study aimed to characterize the inflammatory profile of systemically healthy children's saliva and its association with clinical diagnoses of caries and gingival inflammation. Materials And Methods: Unstimulated saliva...
3.
Dey G, Sinai-Turyansky R, Yakobovich E, Merquiol E, Loboda J, Sridharan N, et al.
Adv Sci (Weinh)
. 2024 Jul;
11(38):e2401518.
PMID: 38970171
Cathepsin-K (CTSK) is an osteoclast-secreted cysteine protease that efficiently cleaves extracellular matrices and promotes bone homeostasis and remodeling, making it an excellent therapeutic target. Detection of CTSK activity in complex...
4.
Polak D, Falcoff D, Chackartchi T, Asher R, Assad R
Int J Oral Maxillofac Implants
. 2023 Nov;
(3):473-478.
PMID: 37939240
Background: Platelet-rich fibrin (PRF) is used to prepare "sticky bone" by combining it with bone graft material. The present study investigated the ability of different bone grafts to absorb growth...
5.
Chachartchi T, Itai Y, Tzach-Nahman R, Sculean A, Shapira L, Polak D
Clin Oral Investig
. 2023 Sep;
27(10):5853-5863.
PMID: 37775586
Objective: To investigate the functional changes of PDL fibroblasts in the presence of mechanical force, inflammation, or a combination of force and inflammation. Materials And Methods: Inflammatory supernatants were prepared...
6.
Halloun B, Hashai K, Pinto N, Musai N, Klein Y, Polak D
iScience
. 2023 Aug;
26(8):106430.
PMID: 37588165
The study investigates the interplay of neutrophils and natural-killer cells (NK) in mediating osseoresorption during infection of molar-incisor-pattern-periodontitis (MIPP). Human neutrophils from periodontally healthy and MIPP patients were inoculated with...
7.
Hashai K, Abadi F, Clyman D, Shany-Kdoshim S, Polak D
J Periodontal Res
. 2023 Jul;
58(5):997-1005.
PMID: 37448100
Objective: The study examines how neutrophils cross-talk with macrophages during JP2 Aggregatibacter actinomycetemcomitance infection and factors that are involved in inflammatory resolution and efferocytosis. Background: Although sub-gingival bacteria constitute the...
8.
Pinto N, Klein Y, David E, Polak D, Steinberg D, Mizrahi G, et al.
Front Immunol
. 2023 Mar;
14:1086930.
PMID: 36923414
Introduction: Allografts are the most common bone grafts for repairing osseous defects. However, their use is associated with an increased risk for infections, donor disease transmission and osteointegration deficiency. Resolvin...
9.
Chackartchi T, Zaydel L, Shapira L, Shany-Kdoshim S, Polak D
J Periodontol
. 2022 Nov;
94(3):419-428.
PMID: 36321648
Background: The aim of the study was to characterize pathogenic biofilm formation on titanium surfaces, the ability to remove the biofilm and the osteoblast response to infected and cleaned titanium...
10.
Klein Y, Levin-Talmor O, Berkstein J, Wald S, Meirow Y, Maimon A, et al.
Front Immunol
. 2022 Oct;
13:928132.
PMID: 36275768
The study aimed to investigate the role of RvD1 in acute and prolonged sterile inflammation and bone remodeling. A mouse model of sterile inflammation that involves bone resorption was used...