David Pim
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Explore the profile of David Pim including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
1129
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0
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Recent Articles
1.
Basukala O, Trejo-Cerro O, Myers M, Pim D, Massimi P, Thomas M, et al.
mBio
. 2022 Oct;
13(6):e0230222.
PMID: 36255238
Human papillomavirus (HPV) E7 plays a major role in HPV-induced malignancy, perturbing cell cycle regulation, and driving cell proliferation. Major targets of cancer-causing HPV E7 proteins are the pRB family...
2.
Bugnon Valdano M, Massimi P, Broniarczyk J, Pim D, Myers M, Gardiol D, et al.
J Virol
. 2021 Mar;
95(11).
PMID: 33731457
Human papillomavirus (HPV) infection is a multi-step process that implies complex interactions of the viral particles with cellular proteins. The HPV capsid includes the two structural proteins L1 and L2,...
3.
Pim D, Broniarczyk J, Siddiqa A, Massimi P, Banks L
J Virol
. 2020 Nov;
95(3).
PMID: 33177206
Previous studies have identified an interaction between the human papillomavirus (HPV) L2 minor capsid protein and sorting nexins 17 and 27 (SNX17 and SNX27) during virus infection. Further studies show...
4.
Siddiqa A, Massimi P, Pim D, Banks L
Front Cell Infect Microbiol
. 2019 Jun;
9:175.
PMID: 31192164
Previous studies have shown that the endoplasmic reticulum (ER)-anchored protein VAP is strictly required by human papillomavirus type 16 (HPV-16) for successful infectious entry. Entry appeared to be mediated in...
5.
Bugnon Valdano M, Pim D, Banks L
Curr Opin Cell Biol
. 2019 May;
59:112-120.
PMID: 31128386
To infect mammalian cells, all infectious viruses must cross a common set of biophysical membrane barriers to gain access to the cell. The virus capsid proteins attach to a host...
6.
Broniarczyk J, Massimi P, Pim D, Bergant Marusic M, Myers M, Garcea R, et al.
J Virol
. 2019 Apr;
93(13).
PMID: 30996086
The human papillomavirus (HPV) capsid comprises two viral proteins, L1 and L2, with the L2 component being essential to ensure efficient endocytic transport of incoming viral genomes. Several studies have...
7.
Law P, Boon S, Hu C, Lung R, Cheung G, Ho W, et al.
J Cell Mol Med
. 2018 Dec;
23(2):1517-1527.
PMID: 30575267
Human papillomavirus 58 (HPV58) ranks the second or third in East Asian cervical cancers. Current studies on HPV58 are scarce and focus on the prototype. Previously, we identified the three...
8.
Siddiqa A, Massimi P, Pim D, Broniarczyk J, Banks L
J Virol
. 2018 Jan;
92(6).
PMID: 29321327
Human papillomavirus (HPV) infection involves complex interactions with the endocytic transport machinery, which ultimately facilitates the entry of the incoming viral genomes into the -Golgi network (TGN) and their subsequent...
9.
McNally K, Faulkner R, Steinberg F, Gallon M, Ghai R, Pim D, et al.
Nat Cell Biol
. 2017 Sep;
19(10):1214-1225.
PMID: 28892079
Following endocytosis into the endosomal network, integral membrane proteins undergo sorting for lysosomal degradation or are retrieved and recycled back to the cell surface. Here we describe the discovery of...
10.
Bergant M, Peternel S, Pim D, Broniarczyk J, Banks L
J Gen Virol
. 2017 May;
98(4):715-725.
PMID: 28475030
The human papillomavirus (HPV) L2 capsid protein plays an essential role during the early stages of viral infection. Previous studies have shown that the interaction between HPV L2 and endosomal...