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David Pfander

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Articles 20
Citations 515
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Recent Articles
1.
Rieber H, Frontzek A, Alefeld M, Heinrich S, Barden B, Jerosch J, et al.
Anaerobe . 2020 Feb; 62:102152. PMID: 32001335
Background: In microbiological diagnosis of periprosthetic joint infection (PJI) there is much controversial discussion about culture media and incubation time, especially if anaerobic bacteria are the causative agents. This retrospective...
2.
Mueller L, Nowak T, Haeberle L, Mueller L, Kress A, Voelk M, et al.
Acta Orthop . 2010 Feb; 81(2):171-7. PMID: 20180716
Background: Aseptic implant loosening and periprosthetic bone loss are major problems after total hip arthroplasty (THA). We present an in vivo method of computed tomography (CT) assisted osteodensitometry after THA...
3.
Daskalow K, Pfander D, Weichert W, Rohwer N, Thelen A, Neuhaus P, et al.
Histochem Cell Biol . 2009 Apr; 132(1):21-31. PMID: 19350262
Hepatocellular carcinoma (HCC) represents the sixth most frequent human cancer worldwide and is characterized by rapid progression as well as resistance to systemic chemotherapy. Recently, glycolysis has emerged as a...
4.
Rohwer N, Welzel M, Daskalow K, Pfander D, Wiedenmann B, Detjen K, et al.
Cancer Res . 2008 Dec; 68(24):10113-20. PMID: 19074877
The transcription factor hypoxia-inducible factor 1 (HIF-1) alpha is abundantly expressed in the majority of human carcinomas and their metastases. HIF-1alpha controls central metastasis-associated pathways such as glycolysis, angiogenesis, and...
5.
Gelse K, Pfander D, Obier S, Knaup K, Wiesener M, Hennig F, et al.
Arthritis Res Ther . 2008 Sep; 10(5):R111. PMID: 18789153
Introduction: Chondrocytes have to withstand considerable hypoxic conditions within the avascular articular cartilage. The present study investigated the effects of inhibiting or stabilizing hypoxia-inducible factor (HIF)-1 alpha by 2-methoxyestradiol or...
6.
Mueller L, Schmidt R, Ehrmann C, Nowak T, Kress A, Forst R, et al.
J Orthop Res . 2008 Aug; 27(2):176-82. PMID: 18752277
Stress-shielding and periprosthetic bone loss after total hip arthroplasty (THA) may be clinically relevant for high-demand patients. Analysis of cortical and cancellous bone density (BD) changes in vivo after THA...
7.
Pfander D, Gelse K
Curr Opin Rheumatol . 2007 Sep; 19(5):457-62. PMID: 17762611
Purpose Of Review: This review summarizes the current knowledge about hypoxia and hypoxia-inducible factor-1 (HIF-1) for chondrocyte survival, energy generation and matrix synthesis of articular chondrocytes during cartilage homeostasis and...
8.
Mueller L, Nowak T, Mueller L, Schmidt R, Ehrmann C, Pitto R, et al.
Arch Orthop Trauma Surg . 2007 Mar; 127(10):909-17. PMID: 17372748
Introduction: The aim of this prospective study was to evaluate load-transfer mechanisms and stress patterns of periacetabular cortical and cancellous bone after cemented total hip arthroplasty (THA) in vivo using...
9.
Mueller L, Degreif J, Schmidt R, Pfander D, Forst R, Rommens P, et al.
Spine (Phila Pa 1976) . 2006 Sep; 31(20):E739-46. PMID: 16985441
Study Design: Computed tomography aided evaluation of spinal decompression by ultrasound-guided spinal fracture repositioning, ligamentotaxis, and remodeling after thoracolumbar burst fractures. Objectives: To determine the necessity of spinal canal widening...
10.
Muller L, Nowak T, Volk M, Pitto R, Pfander D, Forst R, et al.
Biomed Tech (Berl) . 2006 Sep; 51(3):139-44. PMID: 16961457
Aims: We prospectively analyzed the cancellous and cortical periprosthetic femoral bone reaction after implantation of a cementless total hip arthroplasty with computertomography assisted osteodensitometry after a mean of 1 and...