David Perrais
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Explore the profile of David Perrais including associated specialties, affiliations and a list of published articles.
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2446
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Recent Articles
1.
Dantzer C, Vache J, Brunel A, Mahouche I, Raymond A, Dupuy J, et al.
Elife
. 2024 Jul;
13.
PMID: 39008536
Immune checkpoint inhibitors have produced encouraging results in cancer patients. However, the majority of ß-catenin-mutated tumors have been described as lacking immune infiltrates and resistant to immunotherapy. The mechanisms by...
2.
De Koninck Y, Alonso J, Bancelin S, Beique J, Belanger E, Bouchard C, et al.
Neurophotonics
. 2024 Mar;
11(1):014415.
PMID: 38545127
The Frontiers in Neurophotonics Symposium is a biennial event that brings together neurobiologists and physicists/engineers who share interest in the development of leading-edge photonics-based approaches to understand and manipulate the...
3.
Bolz S, Kaempf N, Puchkov D, Krauss M, Russo G, Soykan T, et al.
Neuron
. 2023 Dec;
111(23):3900.
PMID: 38061332
No abstract available.
4.
Bolz S, Kaempf N, Puchkov D, Krauss M, Russo G, Soykan T, et al.
Neuron
. 2023 Sep;
111(23):3765-3774.e7.
PMID: 37738980
Exocytosis and endocytosis are essential physiological processes and are of prime importance for brain function. Neurotransmission depends on the Ca-triggered exocytosis of synaptic vesicles (SVs). In neurons, exocytosis is spatiotemporally...
5.
Perrais D, Sposini S, Angibaud J
Neurophotonics
. 2023 Aug;
10(4):044404.
PMID: 37547562
Membrane trafficking of post-synaptic cargo is a key determinant of synaptic transmission and synaptic plasticity. We describe here the latest developments in visualizing individual exocytosis and endocytosis events in neurons...
6.
Shen Y, Wen Y, Sposini S, Vishwanath A, Abdelfattah A, Schreiter E, et al.
ACS Sens
. 2023 Jul;
8(8):3014-3022.
PMID: 37481776
Genetically encoded pH sensors based on fluorescent proteins are valuable tools for the imaging of cellular events that are associated with pH changes, such as exocytosis and endocytosis. Superecliptic pHluorin...
7.
Perrais D
Biosci Rep
. 2022 Sep;
42(11).
PMID: 36156116
Dynamin is one of the major proteins involved in endocytosis. First identified 50 years ago in a genetic screen in Drosophila melanogaster, it has become a central player in many...
8.
Eichel K, Uenaka T, Belapurkar V, Lu R, Cheng S, Pak J, et al.
Nature
. 2022 Aug;
609(7925):128-135.
PMID: 35978188
Neurons are highly polarized cells that face the fundamental challenge of compartmentalizing a vast and diverse repertoire of proteins in order to function properly. The axon initial segment (AIS) is...
9.
Paget-Blanc V, Pfeffer M, Pronot M, Lapios P, Angelo M, Walle R, et al.
Nat Commun
. 2022 Jun;
13(1):3102.
PMID: 35660742
Dopamine transmission is involved in reward processing and motor control, and its impairment plays a central role in numerous neurological disorders. Despite its strong pathophysiological relevance, the molecular and structural...
10.
Laporte M, Chi K, Caudal L, Zhao N, Schwarz Y, Rolland M, et al.
PLoS Biol
. 2022 Jun;
20(6):e3001659.
PMID: 35658004
In chemical synapses undergoing high frequency stimulation, vesicle components can be retrieved from the plasma membrane via a clathrin-independent process called activity-dependent bulk endocytosis (ADBE). Alix (ALG-2-interacting protein X/PDCD6IP) is...