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David Mullane

Explore the profile of David Mullane including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 198
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Recent Articles
1.
Joyce S, Carey B, Moore N, Mullane D, Moore M, McEntee M, et al.
Pediatr Radiol . 2021 Mar; 51(4):544-553. PMID: 33743038
Thoracic computed tomography (CT) is the imaging reference method in the diagnosis, assessment and management of lung disease. In the setting of cystic fibrosis (CF), CT demonstrates increased sensitivity compared...
2.
Einarsson G, Ronan N, Mooney D, McGettigan C, Mullane D, NiChroinin M, et al.
J Cyst Fibros . 2021 Feb; 20(5):747-753. PMID: 33549519
Background: Treatment with Ivacaftor provides a significant clinical benefit in people with cystic fibrosis (PWCF) with the class III G551D-CFTR mutation. This study determined the effect of CFTR modulation with...
3.
Fitzgerald C, Linnane B, George S, Ni Chroinin M, Mullane D, Herzig M, et al.
Pediatr Pulmonol . 2020 May; 55(9):2323-2329. PMID: 32470170
The introduction of NBS in Ireland in July 2011, provided a unique opportunity to investigate clinical outcomes using a comparative historical cohort study. Clinical cohort: children clinically diagnosed with CF...
4.
Kirwan L, Fletcher G, Harrington M, Jeleniewska P, Zhou S, Casserly B, et al.
Ann Am Thorac Soc . 2018 Nov; 16(2):209-216. PMID: 30427731
Rationale: Patient registries have the potential to collect and analyze high-quality postauthorization data on new medicines. Objectives: We used cystic fibrosis (CF) registry data to assess outcomes after the initiation...
5.
Ronan N, Einarsson G, Twomey M, Mooney D, Mullane D, NiChroinin M, et al.
Chest . 2017 Oct; 153(2):395-403. PMID: 29037527
Background: Ivacaftor produces significant clinical benefit in patients with cystic fibrosis (CF) with the G551D mutation. Prevalence of this mutation at the Cork CF Centre is 23%. This study assessed...
6.
Reen F, Flynn S, Woods D, Dunphy N, Ni Chroinin M, Mullane D, et al.
Sci Rep . 2016 Jul; 6:29768. PMID: 27432520
Despite aggressive antimicrobial therapy, many respiratory pathogens persist in the lung, underpinning the chronic inflammation and eventual lung decline that are characteristic of respiratory disease. Recently, bile acid aspiration has...
7.
Howlett C, Ronan N, NiChroinin M, Mullane D, Plant B
Lancet Respir Med . 2016 Jun; 4(5):e21-2. PMID: 27304562
No abstract available.
8.
Mullane D, Turner S, Cox D, Cox D, Goldblatt J, Landau L, et al.
JAMA Pediatr . 2013 Feb; 167(4):368-73. PMID: 23420147
Unlabelled: IMPORTANCE This is the first study to link reduced lung function in early life, before the development of symptoms, to wheeze in 18-year-olds. Additionally, the study gives insight into...
9.
OConnell O, McWilliams S, McGarrigle A, OConnor O, Shanahan F, Mullane D, et al.
Chest . 2011 Dec; 141(6):1575-1583. PMID: 22207674
Objective: With the increasing life expectancy for patients with cystic fibrosis (CF), and a known predisposition to certain cancers, cumulative radiation exposure from radiologic imaging is of increasing significance. This...
10.
Sutanto E, Kicic A, Foo C, Stevens P, Mullane D, Knight D, et al.
Am J Respir Cell Mol Biol . 2011 Feb; 44(6):761-7. PMID: 21317379
There is controversy regarding whether cystic fibrosis (CF) airway epithelial cells (AECs) are intrinsically proinflammatory. The objective of the current study was to characterize the inflammatory profiles of AECs from...