David Mayleben
Overview
Explore the profile of David Mayleben including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
335
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0
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Recent Articles
1.
Mayleben D, Rosenberg R, Pinner K, Hussein Z, Moline M
Sleep Adv
. 2023 May;
2(1):zpab011.
PMID: 37193566
Objective: To evaluate effects of lemborexant (LEM), a dual orexin receptor antagonist, on next-morning sleep propensity assessed by a modified Multiple Sleep Latency Test (M-MSLT) in adults with insomnia disorder....
2.
Mignot E, Mayleben D, Fietze I, Leger D, Zammit G, Bassetti C, et al.
Lancet Neurol
. 2022 Jan;
21(2):125-139.
PMID: 35065036
Background: Daytime functioning is impaired in people with insomnia disorder. Currently available dual orexin receptor antagonists have shown efficacy in insomnia disorder, but do not address all aspects of this...
3.
Moline M, Zammit G, Cheng J, Perdomo C, Kumar D, Mayleben D
J Clin Sleep Med
. 2021 Feb;
17(6):1167-1174.
PMID: 33590823
Study Objectives: Changes to sleep architecture that occur as a result of the normal aging process may also exacerbate insomnia in older individuals. Therefore, this study assessed the impact of...
4.
Dauvilliers Y, Zammit G, Fietze I, Mayleben D, Seboek Kinter D, Pain S, et al.
Ann Neurol
. 2020 Jan;
87(3):347-356.
PMID: 31953863
Objective: To evaluate the dose-response relationship of daridorexant, a new dual orexin receptor antagonist, on sleep variables in subjects with insomnia disorder. Methods: Adults (≤64 years) with insomnia disorder were...
5.
Rosenberg R, Murphy P, Zammit G, Mayleben D, Kumar D, Dhadda S, et al.
JAMA Netw Open
. 2019 Dec;
2(12):e1918254.
PMID: 31880796
Importance: Insomnia disorder is prevalent and associated with health risks in older adults; however, efficacy and safety issues with existing treatments create significant unmet needs in this patient population. Objective:...
6.
Roth T, Mayleben D, Feldman N, Lankford A, Grant T, Nofzinger E
Sleep
. 2018 Apr;
41(5).
PMID: 29648642
Study Objectives: Insomnia is one of the most common disorders in the general population. Hypnotic medications are efficacious, but their use is limited by adverse events (AEs). This study evaluated...
7.
Murphy P, Moline M, Mayleben D, Rosenberg R, Zammit G, Pinner K, et al.
J Clin Sleep Med
. 2017 Oct;
13(11):1289-1299.
PMID: 29065953
Study Objectives: To identify dose(s) of lemborexant that maximize insomnia treatment efficacy while minimizing next-morning residual sleepiness and evaluate lemborexant effects on polysomnography (PSG) measures (sleep efficiency [SE], latency to...
8.
Struyk A, Gargano C, Drexel M, Stoch S, Svetnik V, Ma J, et al.
Eur Neuropsychopharmacol
. 2016 Aug;
26(10):1649-56.
PMID: 27554636
The objective of this study was to evaluate sleep electrophysiology in healthy subjects after bedtime administration of therapeutic doses of two insomnia treatments - the orexin receptor antagonist suvorexant or...
9.
Simen A, Ma J, Svetnik V, Mayleben D, Maynard J, Roth A, et al.
J Sleep Res
. 2014 Aug;
24(1):66-73.
PMID: 25113527
Non-nucleoside reverse transcriptase inhibitors are important antiretroviral agents for the treatment of human immunodeficiency virus. Some non-nucleoside reverse transcriptase inhibitors, in particular efavirenz, have prominent effects on sleep, cognition and...
10.
Roth T, Zammit G, Lankford A, Mayleben D, Stern T, Pitman V, et al.
Sleep
. 2010 Apr;
33(4):449-58.
PMID: 20394313
Study Objectives: Explore characteristics of nonrestorative sleep (NRS) in prospectively defined subgroups of individuals with NRS symptoms, investigate whether NRS can occur independently of difficulties initiating and maintaining sleep (DIS/DMS),...