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David M Wilson 3rd

Explore the profile of David M Wilson 3rd including associated specialties, affiliations and a list of published articles. Areas
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Articles 140
Citations 5818
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Recent Articles
1.
Scheijen E, Veeningen N, Duwe S, Ivanova A, Van Broeckhoven J, Hendrix S, et al.
J Biomed Sci . 2025 Jan; 32(1):12. PMID: 39844195
Background: Deficient DNA repair and excessive DNA damage contribute to neurodegenerative disease. However, the role of DNA damage and repair in spinal cord injury (SCI) is unclear. SCI, a debilitating...
2.
Mombeek L, Boesmans W, Wilson 3rd D
Neurogastroenterol Motil . 2024 Jul; :e14860. PMID: 39004995
This review discusses the less-explored realm of DNA damage and repair within the enteric nervous system (ENS), often referred to as the "second brain." While the central nervous system has...
3.
Kisby G, Wilson 3rd D, Spencer P
Int J Mol Sci . 2024 Jul; 25(13). PMID: 39000326
Decades of research have identified genetic and environmental factors involved in age-related neurodegenerative diseases and, to a lesser extent, neuropsychiatric disorders. Genomic instability, i.e., the loss of genome integrity, is...
4.
Neven J, Issayama L, Dewachter I, Wilson 3rd D
DNA Repair (Amst) . 2024 Apr; 139:103678. PMID: 38669748
Alzheimer disease (AD) is the most prominent form of dementia and has received considerable attention due to its growing burden on economic, healthcare and basic societal infrastructures. The two major...
5.
Das D, Duncton M, Georgiadis T, Pellicena P, Clark J, Sobol R, et al.
Int J Mol Sci . 2023 Dec; 24(23). PMID: 38068959
The ability to quickly discover reliable hits from screening and rapidly convert them into lead compounds, which can be verified in functional assays, is central to drug discovery. The expedited...
6.
Singh A, Schurman S, Bektas A, Kaileh M, Roy R, Wilson 3rd D, et al.
Cold Spring Harb Perspect Med . 2023 Dec; 14(6). PMID: 38052484
Aging can be conceptualized as the progressive disequilibrium between stochastic damage accumulation and resilience mechanisms that continuously repair that damage, which eventually cause the development of chronic disease, frailty, and...
7.
Ferrucci L, Wilson 3rd D, Donega S, Montano M
Aging Cell . 2023 Dec; 23(1):e14034. PMID: 38038340
Geroscience poses that core biological mechanisms of aging contribute to chronic diseases and disabilities in late life and that health span and longevity can be modulated by pharmacological and behavioral...
8.
Ferrucci L, Wilson 3rd D, Donega S, Gorospe M
Nat Aging . 2023 Apr; 2(3):182-185. PMID: 37118371
No abstract available.
9.
Wilson 3rd D, Cookson M, Van Den Bosch L, Zetterberg H, Holtzman D, Dewachter I
Cell . 2023 Feb; 186(4):693-714. PMID: 36803602
Decades of research have identified genetic factors and biochemical pathways involved in neurodegenerative diseases (NDDs). We present evidence for the following eight hallmarks of NDD: pathological protein aggregation, synaptic and...
10.
Thomas J, Bruzzone R, El-Osta A, Claessens F, Ruysschaert J, Wilson 3rd D
Cell Mol Life Sci . 2022 Sep; 79(10):529. PMID: 36166158
No abstract available.