David M van Reyk
Overview
Explore the profile of David M van Reyk including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
226
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Recent Articles
1.
Pan G, Rayner B, Zhang Y, van Reyk D, Hawkins C
Arch Biochem Biophys
. 2018 Feb;
642:23-30.
PMID: 29410057
Atherosclerosis is characterised by the infiltration of macrophages at sites of inflammation within the vessel wall and the release of myeloperoxidase (MPO), which forms hypochlorous acid (HOCl) and hypothiocyanous acid...
2.
Abdo A, Rayner B, van Reyk D, Hawkins C
Redox Biol
. 2017 Aug;
13:623-632.
PMID: 28818791
Low-density lipoprotein (LDL) modified by hypochlorous acid (HOCl) produced by myeloperoxidase (MPO) is present in atherosclerotic lesions, where it is implicated in the propagation of inflammation and acceleration of lesion...
3.
Kim C, Mitchell J, Bursill C, Sowers A, Thetford A, Cook J, et al.
Atherosclerosis
. 2015 Mar;
240(1):234-41.
PMID: 25818249
Objective: The nitroxide compound TEMPOL (4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl radical) has been shown to prevent obesity-induced changes in adipokines in cell and animal systems. In this study we investigated whether supplementation with TEMPOL...
4.
Ismael F, Proudfoot J, Brown B, van Reyk D, Croft K, Davies M, et al.
Arch Biochem Biophys
. 2015 Mar;
573:40-51.
PMID: 25795019
Atherosclerosis is characterised by the accumulation of lipids within macrophages in the artery wall. Low-density lipoprotein (LDL) is the source of this lipid, owing to the uptake of oxidised LDL...
5.
Brown B, Kim C, Torpy F, Bursill C, McRobb L, Heather A, et al.
Atherosclerosis
. 2014 Jan;
232(2):403-9.
PMID: 24468155
Objective: Carnosine has been shown to modulate triglyceride and glycation levels in cell and animal systems. In this study we investigated whether prolonged supplementation with carnosine inhibits atherosclerosis and markers...
6.
Moheimani F, Kim C, Suryo Rahmanto A, van Reyk D, Davies M
Atherosclerosis
. 2012 Jun;
223(1):144-51.
PMID: 22658253
Objective: People with diabetes have an elevated risk of atherosclerosis. The accumulation of lipid within macrophage cells in the artery wall is believed to arise via the uptake and subsequent...
7.
Moheimani F, Tan J, Brown B, Heather A, van Reyk D, Davies M
Exp Diabetes Res
. 2011 Sep;
2011:851280.
PMID: 21904540
During atherosclerosis monocyte-derived macrophages accumulate cholesteryl esters from low-density lipoproteins (LDLs) via lectin-like oxidised LDL receptor-1 (LOX-1) and class AI and AII (SR-AI, SR-AII) and class B (SR-BI, CD36) scavenger...
8.
Moheimani F, Morgan P, van Reyk D, Davies M
Biochim Biophys Acta
. 2010 Feb;
1802(6):561-71.
PMID: 20176104
People with diabetes experience chronic hyperglycemia and are at a high risk of developing atherosclerosis and microvascular disease. Reactions of glucose, or aldehydes derived from glucose (e.g. methylglyoxal, glyoxal, or...
9.
Lloyd M, van Reyk D, Davies M, Hawkins C
Biochem J
. 2008 May;
414(2):271-80.
PMID: 18459943
Hypohalous acids are generated by activated leucocytes, via the formation of H(2)O(2) and the release of peroxidase enzymes (myeloperoxidase and eosinophil peroxidase). These species are important bactericidal agents, but HOCl...
10.
Brown B, Rashid I, van Reyk D, Davies M
FEBS J
. 2007 May;
274(6):1530-41.
PMID: 17480204
Nonenzymatic covalent binding (glycation) of reactive aldehydes (from glucose or metabolic processes) to low-density lipoproteins has been previously shown to result in lipid accumulation in a murine macrophage cell line....