David M Systrom
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Explore the profile of David M Systrom including associated specialties, affiliations and a list of published articles.
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68
Citations
1996
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Recent Articles
1.
Vasoreactivity and inhaled treprostinil response in interstitial lung disease pulmonary hypertension
Harder E, Rahaghi F, Leopold J, Systrom D, Washko G, Waxman A
ERJ Open Res
. 2024 Dec;
10(6).
PMID: 39624389
Introduction: Despite shared features with pulmonary arterial hypertension, acute vasoreactivity in pulmonary hypertension with interstitial lung disease (PH-ILD) is not well characterised, including its potential ability to predict therapeutic outcomes....
2.
Novak P, Systrom D, Witte A, Marciano S
Front Neurol
. 2024 Nov;
15:1476918.
PMID: 39544990
Background: Spectrum of chronic orthostatic intolerance without orthostatic hypotension includes postural tachycardia syndrome (POTS), with orthostatic tachycardia and hypocapnic cerebral hypoperfusion (HYCH), without orthostatic tachycardia. This study compared autonomic, cerebrovascular,...
3.
Waxman A, Systrom D, Manimaran S, de Oliveira Pena J, Lu J, Rischard F
Circ Heart Fail
. 2024 Apr;
17(5):e011227.
PMID: 38572639
Background: This study aims to assess the impact of sotatercept on exercise tolerance, exercise capacity, and right ventricular function in pulmonary arterial hypertension. Methods: SPECTRA (Sotatercept Phase 2 Exploratory Clinical...
4.
Novak P, Systrom D, Marciano S, Knief A, Felsenstein D, Giannetti M, et al.
Sci Rep
. 2024 Jan;
14(1):2513.
PMID: 38291116
Autonomic symptom questionnaires are frequently used to assess dysautonomia. It is unknown whether subjective dysautonomia obtained from autonomic questionnaires correlates with objective dysautonomia measured by quantitative autonomic testing. The objective...
5.
Khurshid S, Churchill T, Diamant N, Di Achille P, Reeder C, Singh P, et al.
Eur J Prev Cardiol
. 2023 Oct;
31(2):252-262.
PMID: 37798122
Aims: To leverage deep learning on the resting 12-lead electrocardiogram (ECG) to estimate peak oxygen consumption (V˙O2peak) without cardiopulmonary exercise testing (CPET). Methods And Results: V ˙ O 2 peak...
6.
Slavin M, Bailey H, Hickey E, Vasudevan A, Ledingham A, Tannenbaum L, et al.
PLoS One
. 2023 Sep;
18(9):e0291364.
PMID: 37698999
Introduction: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a multisystem chronic disease estimated to affect 836,000-2.5 million individuals in the United States. Persons with ME/CFS have a substantial reduction in their...
7.
Joseph P, Singh I, Oliveira R, Capone C, Mullen M, Cook D, et al.
Chest
. 2023 Apr;
164(3):717-726.
PMID: 37054777
Topic Importance: Postacute sequelae of SARS-CoV-2 (PASC) is a long-term consequence of acute infection from COVID-19. Clinical overlap between PASC and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) has been observed, with...
8.
Winkler T, Kohli P, Kelly V, Kehl E, Witkin A, Rodriguez-Lopez J, et al.
Respir Res
. 2022 Dec;
23(1):325.
PMID: 36457013
Background: Without aggressive treatment, pulmonary arterial hypertension (PAH) has a 5-year mortality of approximately 40%. A patient's response to vasodilators at diagnosis impacts the therapeutic options and prognosis. We hypothesized...
9.
Joseph P, Pari R, Miller S, Warren A, Stovall M, Squires J, et al.
Chest
. 2022 May;
162(5):1116-1126.
PMID: 35526605
Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by intractable fatigue, postexertional malaise, and orthostatic intolerance, but its pathophysiology is poorly understood. Pharmacologic cholinergic stimulation was used to test the...
10.
Singh I, Joseph P, Heerdt P, Cullinan M, Lutchmansingh D, Gulati M, et al.
Chest
. 2021 Aug;
161(1):54-63.
PMID: 34389297
Background: Some patients with COVID-19 who have recovered from the acute infection after experiencing only mild symptoms continue to exhibit persistent exertional limitation that often is unexplained by conventional investigative...