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David M Patrick

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Articles 185
Citations 4145
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Recent Articles
1.
Lee T, Petkau J, Saatchi A, Marra F, Turvey S, Lishman H, et al.
Front Allergy . 2025 Jan; 5:1491985. PMID: 39764437
Background: Infant antibiotic use is associated with increased risk of asthma. We examined the population impact of antibiotic exposure in the first year of life on the burden of pediatric...
2.
Stenlund S, Huynh J, Pau C, Chuang E, Lishman H, Patrick D
J Am Dent Assoc . 2024 Nov; 156(1):37-45.e7. PMID: 39556074
Background: Dentists in the United States and Canada have higher rates of prescribing broad-spectrum spectrum antibiotics than dentists in some other Western countries. The authors provide an overview of dental...
3.
Carney G, MacLure M, Patrick D, Otte J, Ambasta A, Thompson W, et al.
BMJ Qual Saf . 2024 Oct; PMID: 39414374
Objective: To evaluate the impact of a personalised audit and feedback prescribing report (AF) and brief educational summary (ES) on empiric treatment of uncomplicated lower urinary tract infections (UTIs) by...
4.
Al Mamun A, Zou C, Lishman H, Stenlund S, Xie M, Chuang E, et al.
Front Allergy . 2024 Sep; 5:1456077. PMID: 39286476
Background: This study follows published associations in BC to 2014 (updated in 2019) to model the predicted incidence of asthma in BC children attributable to antibiotic use within the context...
5.
Stenlund S, Appelt K, Ruby M, Smith N, Lishman H, Patrick D
Antibiotics (Basel) . 2024 Jul; 13(7). PMID: 39061339
Patients' expectations are a major contributor to the unnecessary prescribing of antibiotics, yet limited research has examined how physicians can calibrate these expectations. The studies we conducted tested how varying...
6.
Harrison D, Patrick D
Hypertension . 2024 Jun; 81(8):1659-1674. PMID: 38881474
It is now apparent that immune mediators including complement, cytokines, and cells of the innate and adaptive immune system contribute not only to blood pressure elevation but also to the...
7.
Krishnan J, Hennen E, Ao M, Kirabo A, Ahmad T, de la Visitacion N, et al.
Circ Res . 2024 Apr; 134(11):1483-1494. PMID: 38666386
Background: Neutrophil extracellular traps (NETs) are composed of DNA, enzymes, and citrullinated histones that are expelled by neutrophils in the process of NETosis. NETs accumulate in the aorta and kidneys...
8.
de la Visitacion N, Chen W, Krishnan J, Van Beusecum J, Amarnath V, Hennen E, et al.
Circ Res . 2024 Apr; 134(10):1276-1291. PMID: 38623763
Background: Hypertension is characterized by CD8 (cluster differentiation 8) T cell activation and infiltration into peripheral tissues. CD8 T cell activation requires proteasomal processing of antigenic proteins. It has become...
9.
Lee C, Banoei M, Ansari M, Cheng M, Lamontagne F, Griesdale D, et al.
Crit Care . 2024 Feb; 28(1):63. PMID: 38414082
Rationale: Acute respiratory distress syndrome (ARDS) is a life-threatening critical care syndrome commonly associated with infections such as COVID-19, influenza, and bacterial pneumonia. Ongoing research aims to improve our understanding...
10.
Nikiforuk A, Kuchinski K, Short K, Roman S, Irvine M, Prystajecky N, et al.
BMC Infect Dis . 2024 Feb; 24(1):262. PMID: 38408924
Background: Widespread human-to-human transmission of the severe acute respiratory syndrome coronavirus two (SARS-CoV-2) stems from a strong affinity for the cellular receptor angiotensin converting enzyme two (ACE2). We investigate the...