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David Luesley

Explore the profile of David Luesley including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 583
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Recent Articles
1.
Oonk M, Slomovitz B, Baldwin P, van Doorn H, van der Velden J, de Hullu J, et al.
J Clin Oncol . 2021 Aug; 39(32):3623-3632. PMID: 34432481
Purpose: The Groningen International Study on Sentinel nodes in Vulvar cancer (GROINSS-V)-II investigated whether inguinofemoral radiotherapy is a safe alternative to inguinofemoral lymphadenectomy (IFL) in vulvar cancer patients with a...
2.
Yap J, Fox R, Narsia N, Pinheiro-Maia S, Pounds R, Woodman C, et al.
PLoS One . 2018 Nov; 13(10):e0206553. PMID: 30379908
Objective: Dysregulation of the Hedgehog (Hh) pathway has been described in a variety of cancers, including cervical cancer, a disease which shares a common aetiology with vulval squamous cell carcinoma...
3.
Pounds R, Tahir S, Dawson C, Woodman C, Luesley D, Yap J
J Obstet Gynaecol . 2017 Oct; 38(2):265-269. PMID: 29017363
Evidence suggests that lichen sclerosus (LS) is the primary aetiological factor for local vulval recurrence (LVR) in vulval squamous cell carcinoma (VSCC). The long-term application of topical corticosteroids is believed...
4.
Leonard S, Pereira M, Fox R, Gordon N, Yap J, Kehoe S, et al.
Gynecol Oncol . 2016 Sep; 143(2):414-420. PMID: 27623253
Objective: Cancer initiation and progression has been linked to aberrant expression of the DNA methyltransferases (DNMT), the enzymes which establish and maintain DNA methylation patterns throughout the genome. In this...
5.
Soo-Hoo S, Luesley D
Best Pract Res Clin Obstet Gynaecol . 2015 Nov; 33:73-8. PMID: 26526939
Lower genital tract malignancy during pregnancy is rare. Due to the rarity of this condition, the best evidence in its management is based on case reports. The management of the...
6.
Soo Hoo S, Marriott N, Houlton A, Nevin J, Balega J, Singh K, et al.
Int J Gynecol Cancer . 2015 Sep; 25(9):1599-607. PMID: 26397157
Background: Extensive (ultraradical) surgery may facilitate complete cytoreduction in ovarian cancer with potential survival benefit but with greater morbidity. Currently, patient-reported outcomes (PROs) from such surgery are unknown. We conducted...
7.
Kehoe S, Hook J, Nankivell M, Jayson G, Kitchener H, Lopes T, et al.
Lancet . 2015 May; 386(9990):249-57. PMID: 26002111
Background: The international standard of care for women with suspected advanced ovarian cancer is surgical debulking followed by platinum-based chemotherapy. We aimed to establish whether use of platinum-based primary chemotherapy...
8.
Rogers L, Siu S, Luesley D, Bryant A, Dickinson H
Cochrane Database Syst Rev . 2012 May; (5):CD007583. PMID: 22592722
Background: This is an updated version of the original Cochrane review first published in Issue 4, 2009. There is an ongoing debate about the indications for, and value of, adjuvant...
9.
Flanagan S, Wilson S, Luesley D, Damery S, Greenfield S
BMC Womens Health . 2011 Jan; 11:2. PMID: 21251278
Background: Colposcopy is an essential part of the National Health Service Cervical Screening Programme (NHSCSP). It is used for both diagnosis and treatment of pre-cancerous cells of the cervix. Despite...
10.
Moss E, Owen G, Jones P, Sarhanis P, Nordin A, Luesley D, et al.
Int J Gynecol Cancer . 2010 Aug; 20(4):488-91. PMID: 20686369
Objective: To determine a set of auditable standards applicable to physicians working in the area of gynecological oncology, which could be implemented as accreditation criteria for the revalidation procedure. Design:...