David Leu
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Explore the profile of David Leu including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
268
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Recent Articles
1.
Leu D, Spasojevic I, Nguyen H, Deng B, Tovmasyan A, Weitner T, et al.
Redox Biol
. 2017 Apr;
12:864-871.
PMID: 28454069
Although radiation therapy can be effective against cancer, potential damage to normal tissues limits the amount that can be safely administered. In central nervous system (CNS), radiation damage to normal...
2.
Yang P, Leu D, Ye K, Srinivasan C, Fike J, Huang T
Exp Neurol
. 2016 Mar;
279:178-186.
PMID: 26946222
Brain radiotherapy is frequently used successfully to treat brain tumors. However, radiotherapy is often associated with declines in short-term and long-term memory, learning ability, and verbal fluency. We previously identified...
3.
Tajerian M, Leu D, Yang P, Huang T, Kingery W, Clark J
Anesthesiology
. 2015 Oct;
123(6):1435-47.
PMID: 26492479
Background: Complex regional pain syndrome (CRPS) is a painful, disabling, and often chronic condition, where many patients transition from an acute phase with prominent peripheral neurogenic inflammation to a chronic...
4.
Tajerian M, Sahbaie P, Sun Y, Leu D, Yang H, Li W, et al.
Neurobiol Learn Mem
. 2015 Jun;
123:100-9.
PMID: 26070658
Complex Regional Pain Syndrome (CRPS) is a major cause of chronic pain after surgery or trauma to the limbs. Despite evidence showing that the prevalence and severity of many forms...
5.
Huang T, Leu D, Zou Y
Arch Biochem Biophys
. 2015 Mar;
576:2-7.
PMID: 25797440
Hippocampal-dependent cognitive functions rely on production of new neurons and maintenance of dendritic structures to provide the synaptic plasticity needed for learning and formation of new memories. Hippocampal formation is...
6.
Allen A, Eilertson K, Sharma S, Baure J, Allen B, Leu D, et al.
Radiat Res
. 2014 Nov;
182(5):489-98.
PMID: 25375198
Radiation exposure due to radiological terrorism and military circumstances are a continuing threat for the civilian population. In an uncontrolled radiation event, it is likely that there will be other...
7.
Tajerian M, Leu D, Zou Y, Sahbaie P, Li W, Khan H, et al.
Anesthesiology
. 2014 Aug;
121(4):852-65.
PMID: 25093591
Background: Complex regional pain syndrome (CRPS) is a painful condition with approximately 50,000 annual new cases in the United States. It is a major cause of work-related disability, chronic pain...
8.
Wellman D, Lazaro L, Cymerman R, Axelrad T, Leu D, Helfet D, et al.
J Orthop Trauma
. 2014 May;
29(1):36-43.
PMID: 24824096
Objectives: To evaluate the outcomes of olecranon fractures treated with 2.4- and 2.7-mm plate constructs. Design: Retrospective Case Series. Setting: One-level 1 trauma center and 1 tertiary care hospital. Patients:...
9.
Zou Y, Leu D, Chui J, Fike J, Huang T
Int J Radiat Oncol Biol Phys
. 2013 Sep;
87(4):777-84.
PMID: 24064316
Purpose: Altered levels of extracellular superoxide dismutase (EC-SOD) and cranial irradiation have been shown to affect hippocampal neurogenesis. However, previous studies were only conducted in male mice, and it was...
10.
Zou Y, Corniola R, Leu D, Khan A, Sahbaie P, Chakraborti A, et al.
Proc Natl Acad Sci U S A
. 2012 Dec;
109(52):21522-7.
PMID: 23236175
Cranial irradiation is widely used in cancer therapy, but it often causes cognitive defects in cancer survivors. Oxidative stress is considered a major cause of tissue injury from irradiation. However,...