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David Leiman

Explore the profile of David Leiman including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 16
Citations 102
Followers 0
Related Specialties
Psychiatry
General Surgery
Neurology
Top 10 Co-Authors
Harold S Minkowitz
Neil Singla
Pamela P Palmer
Karen P DiDonato
Harold Minkowitz
Mark Harnett
Scott Reines
Gwendolyn Niebler
Michael Ryan
Lucy Lu
Published In
Plast Reconstr Surg Glob Open
Adv Ther
J Pain Res
J Health Serv Res Policy
Pain Med
Affiliations
Soon will be listed here.
Recent Articles
1.
A Phase I Study of the Pharmacokinetics, Pharmacodynamics, and Safety of Liposomal Bupivacaine for Sciatic Nerve Block in the Popliteal Fossa for Bunionectomy
Sessler D, Bao X, Leiman D, Song J, Chittenden J, Voelkner A, et al.
J Clin Pharmacol . 2024 Nov; PMID: 39520051
This trial assessed the pharmacokinetics, pharmacodynamics, and safety of liposomal bupivacaine given via ultrasound-guided popliteal sciatic nerve block with or without immediate-release bupivacaine hydrochloride in adults having bunionectomies. Forty-five adults...
2.
Safety and Efficacy of Vocacapsaicin for Management of Postsurgical Pain: A Randomized Clinical Trial
Shafer S, Teichman S, Gottlieb I, Singla N, Minkowitz H, Leiman D, et al.
Anesthesiology . 2024 Apr; 141(2):250-261. PMID: 38662910
Background: Nonopioid management of postsurgical pain remains a major unmet need. Few studies have evaluated transient receptor potential vanilloid subfamily member 1 agonists for analgesia after surgery. This study examines...
3.
A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of a bupivacaine hydrochloride implant in patients undergoing abdominoplasty
Beaton A, Solanki D, Salazar H, Folkerth S, Singla N, Minkowitz H, et al.
Reg Anesth Pain Med . 2023 Apr; 48(12):601-607. PMID: 37076252
Introduction: Surgical site infiltration with bupivacaine hydrochloride (HCl) is a standard element of postoperative analgesia for soft tissue surgeries, but results in short-lived analgesia. A novel bupivacaine implant, XARACOLL (bupivacaine...
4.
Patient and Healthcare Professional Satisfaction Ratings and Safety Profile of Sufentanil Sublingual Tablets for Treatment of Acute Pain: A Pooled Demographic Analysis
Leiman D, Jove M, Spahn G, Palmer P
J Pain Res . 2021 Apr; 14:805-813. PMID: 33790642
Objective: This analysis reports the healthcare professional global assessment (HPGA) and patient global assessment (PGA) scores and the adverse event (AE) profile by age, body mass index (BMI), sex, and...
5.
Pharmacokinetics and Safety of INL-001 (Bupivacaine HCl) Implants Compared with Bupivacaine HCl Infiltration After Open Unilateral Inguinal Hernioplasty
Leiman D, Niebler G, Minkowitz H
Adv Ther . 2020 Nov; 38(1):691-706. PMID: 33237534
Introduction: Surgical site infiltration with bupivacaine HCl results in short-lived analgesia for postsurgical pain and carries the risk of systemic bupivacaine toxicity due to accidental intravascular injection. INL-001 is a...
6.
Efficacy and Safety of Intravenously Administered Tramadol in Patients with Moderate to Severe Pain Following Bunionectomy: A Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study
Singla N, Pollak R, Gottlieb I, Leiman D, Minkowitz H, Zimmerman J, et al.
Pain Ther . 2020 Jul; 9(2):545-562. PMID: 32683644
Introduction: This study is part of the registrational program for intravenously administered (IV) tramadol in the USA and compared the analgesic benefit and tolerability of two doses of IV tramadol...
7.
IV Tramadol - A New Treatment Option for Management of Post-Operative Pain in the US: An Open-Label, Single-Arm, Safety Trial Including Various Types of Surgery
Minkowitz H, Leiman D, Lu L, Reines S, Ryan M, Harnett M, et al.
J Pain Res . 2020 Jun; 13:1155-1162. PMID: 32547178
Purpose: There is a need to reduce exposure to Schedule II opioids in the United States (US) due to the ongoing opioid epidemic. Schedule II opioids have higher potential for...
8.
Intravenous Tramadol is Effective in the Management of Postoperative Pain Following Abdominoplasty: A Three-Arm Randomized Placebo- and Active-Controlled Trial
Minkowitz H, Salazar H, Leiman D, Solanki D, Lu L, Reines S, et al.
Drugs R D . 2020 May; 20(3):225-236. PMID: 32409981
Background And Objective: Oral tramadol, an atypical opioid approved in the United States (US) since 1995 and a Schedule IV controlled substance, has less abuse liability compared to Schedule II...
9.
Pooled Dosing and Efficacy Analysis of the Sufentanil Sublingual Tablet 30 mcg Across Demographic Subgroups for the Management of Moderate-to-Severe Acute Pain
Hutchins J, Leiman D, Rafique Z, DiDonato K, Palmer P
J Perianesth Nurs . 2019 Nov; 35(1):22-28. PMID: 31732448
Purpose: To aid nurses in dosing sufentanil sublingual tablet (SST) 30 mcg administered via a single-dose applicator, dosing requirements and efficacy of SST 30 mcg were analyzed across age, sex,...
10.
Pooled Phase III safety analysis of sufentanil sublingual tablets for short-term treatment of moderate-to-severe acute pain
Miner J, Melson T, Leiman D, Minkowitz H, Chiang Y, DiDonato K, et al.
Pain Manag . 2019 Jan; 9(3):259-271. PMID: 30614379
To evaluate the pooled safety of sufentanil sublingual tablets (SSTs) administered at 30-mcg dose equivalents over ≤72 h for moderate-to-severe acute pain management in medically supervised settings. Safety data from...