David Ledbetter
Overview
Explore the profile of David Ledbetter including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
1526
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0
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Recent Articles
1.
A Novel Application of Spectrograms with Machine Learning Can Detect Patient Ventilator Dyssynchrony
Obeso I, Yoon B, Ledbetter D, Aczon M, Laksana E, Zhou A, et al.
Biomed Signal Process Control
. 2023 Aug;
86(Pt C).
PMID: 37587924
Patients in intensive care units are frequently supported by mechanical ventilation. There is increasing awareness of patient-ventilator dyssynchrony (PVD), a mismatch between patient respiratory effort and assistance provided by the...
2.
Pappy G, Aczon M, Wetzel R, Ledbetter D
JMIR Med Inform
. 2022 Mar;
10(3):e31760.
PMID: 35238792
Background: High flow nasal cannula (HFNC) provides noninvasive respiratory support for children who are critically ill who may tolerate it more readily than other noninvasive ventilation (NIV) techniques such as...
3.
Ho L, Aczon M, Ledbetter D, Wetzel R
J Biomed Inform
. 2021 Jan;
114:103672.
PMID: 33422663
Deep learning has demonstrated success in many applications; however, their use in healthcare has been limited due to the lack of transparency into how they generate predictions. Algorithms such as...
4.
Laksana E, Aczon M, Ho L, Carlin C, Ledbetter D, Wetzel R
J Biomed Inform
. 2019 Dec;
102:103351.
PMID: 31870949
Electronic Medical Records (EMR) are a rich source of patient information, including measurements reflecting physiologic signs and administered therapies. Identifying which variables or features are useful in predicting clinical outcomes...
5.
Ledbetter D, Aczon M, Wetzel R
Pediatr Crit Care Med
. 2019 Apr;
20(4):399-400.
PMID: 30951002
No abstract available.
6.
Ho L, Ledbetter D, Aczon M, Wetzel R
AMIA Annu Symp Proc
. 2018 Jun;
2017:883-891.
PMID: 29854155
There is growing interest in applying machine learning methods to Electronic Medical Records (EMR). Across different institutions, however, EMR quality can vary widely. This work investigated the impact of this...
7.
Korf B, Ledbetter D, Murray M
Genet Med
. 2008 Jun;
10(7):502-7.
PMID: 18580691
No abstract available.
8.
Sebat J, Lakshmi B, Malhotra D, Troge J, Lese-Martin C, Walsh T, et al.
Science
. 2007 Mar;
316(5823):445-9.
PMID: 17363630
We tested the hypothesis that de novo copy number variation (CNV) is associated with autism spectrum disorders (ASDs). We performed comparative genomic hybridization (CGH) on the genomic DNA of patients...
9.
Toyo-Oka K, Shionoya A, Gambello M, Cardoso C, Leventer R, Ward H, et al.
Nat Genet
. 2003 Jun;
34(3):274-85.
PMID: 12796778
Heterozygous deletions of 17p13.3 result in the human neuronal migration disorders isolated lissencephaly sequence (ILS) and the more severe Miller-Dieker syndrome (MDS). Mutations in PAFAH1B1 (the gene encoding LIS1) are...